Concurrent validity and reliability of suicide risk assessment instruments: A meta analysis of 20 instruments across 27 international cohorts

Adrian I. Campos; Laura S. Van Velzen; Dick J. Veltman; Elena Pozzi; Sonia Ambrogi; Elizabeth D. Ballard; Nerisa Banaj; Zeynep Başgöze; Sophie Bellow; Francesco Benedetti; Irene Bollettini; Katharina Brosch; Erick J. Canales-Rodríguez; Emily K. Clarke-Rubright; Lejla Colic; Colm G. Connolly; Philippe Courtet; Kathryn R. Cullen; Udo Dannlowski; Maria R. Dauvermann; Christopher G. Davey; Jeremy Deverdun; Katharina Dohm; Tracy Erwin-Grabner; Negar Fani; Lydia Fortea; Paola Fuentes-Claramonte; Ali Saffet Gonul; Ian H. Gotlib; Dominik Grotegerd; Mathew A. Harris; Ben J. Harrison; Courtney C. Haswell; Emma L. Hawkins; Dawson Hill; Yoshiyuki Hirano; Tiffany C. Ho; Fabrice Jollant; Tanja Jovanovic; Tilo Kircher; Bonnie Klimes-Dougan; Emmanuelle le Bars; Christine Lochner; Andrew M. McIntosh; Susanne Meinert; Yara Mekawi; Elisa Melloni; Philip Mitchell; Rajendra A. Morey; Akiko Nakagawa; Igor Nenadić; Emilie Olié; Fabricio Pereira; Rachel D. Phillips; Fabrizio Piras; Sara Poletti; Edith Pomarol-Clotet; Joaquim Radua; Kerry J. Ressler; Gloria Roberts; Elena Rodriguez-Cano; Matthew D. Sacchet; Raymond Salvador; Anca-Larisa Sandu; Eiji Shimizu; Aditya Singh; Gianfranco Spalletta; J. Douglas Steele; Dan J. Stein; Frederike Stein; Jennifer S. Stevens; Giana I. Teresi; Aslihan Uyar-Demir; Nic J. van der Wee; Steven J. van der Werff; Sanne J.H. van Rooij; Daniela Vecchio; Norma Verdolini; Eduard Vieta; Gordon D. Waiter; Heather Whalley; Sarah L. Whittle; Tony T. Yang; Carlos A. Zarate; Paul M. Thompson; Neda Jahanshad; Anne-Laura van Harmelen; Hilary P. Blumberg; Lianne Schmaal; Miguel E. Rentería

doi:10.1101/2021.09.15.21263562

Prépublication

Concurrent validity and reliability of suicide risk assessment instruments: A meta analysis of 20 instruments across 27 international cohorts

Adrian I. Campos, Laura S. Van Velzen, Dick J. Veltman, Elena Pozzi, Sonia Ambrogi, Elizabeth D. Ballard, Nerisa Banaj, Zeynep Başgöze, Sophie Bellow, Francesco Benedetti, …

medRxiv

Cold Spring Harbor Laboratory Press, 1.1

21/09/2021

DOI: https://doi.org/10.1101/2021.09.15.21263562

Résumé

Psychiatry and Clinical Psychology

A major limitation of current suicide research is the lack of power to identify robust correlates of suicidal thoughts or behaviour. Variation in suicide risk assessment instruments used across cohorts may represent a limitation to pooling data in international consortia. Here, we examine this issue through two approaches: (i) an extensive literature search on the reliability and concurrent validity of the most commonly used instruments; and (ii) by pooling data (N∼6,000 participants) from cohorts from the ENIGMA-Major Depressive Disorder (ENIGMA-MDD) and ENIGMA-Suicidal Thoughts and Behaviour (ENIGMA-STB) working groups, to assess the concurrent validity of instruments currently used for assessing suicidal thoughts or behaviour. Our results suggested a pattern of moderate-to-high correlations between instruments, consistent with the wide range of correlations, r=0.22-0.97, reported in the literature. Two common complex instruments, the Columbia Suicide Severity Rating Scale (C-SSRS) and the Beck Scale for Suicidal Ideation (SSI), were highly correlated with each other (r=0.83), as were suicidal ideation items from common depression severity questionnaires. Our findings suggest that multi-item instruments provide valuable information on different aspects of suicidal thoughts or behaviour, but share a core factor with single suicidal ideation items found in depression severity questionnaires. Multi-site collaborations including cohorts that used distinct instruments for suicide risk assessment should be feasible provided that they harmonise across instruments or focus on specific constructs of suicidal thoughts or behaviours. Question: To inform future suicide research in multi-site international consortia, it is important to examine how different suicide measures relate to each other and whether they can be used interchangeably. Findings: Findings suggest detailed instruments (such as the Columbia Suicide Severity Rating Scale and Beck Scale for Suicidal Ideation) provide valuable information on suicidal thoughts and behaviour, and share a core factor with items on suicidal ideation from depression severity rating scale (such as the Hamilton Depression Rating Scale or the Beck Depression Inventory). Importance: Results from international collaborations can mitigate biases by harmonising distinct suicide risk assessment instruments. Next steps: Pooling data within international suicide research consortia may reveal novel clinical, biological and cognitive correlates of suicidal thoughts and/or behaviour.

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Titre: Concurrent validity and reliability of suicide risk assessment instruments: A meta analysis of 20 instruments across 27 international cohorts
Créateurs - sans rôle: Adrian I. Campos - School of Biomedical Sciences, Faculty of Medicine, The University of Queensland
Laura S. Van Velzen - The University of Melbourne
Dick J. Veltman - Vrije Universiteit Amsterdam
Elena Pozzi - The University of Melbourne
Sonia Ambrogi - Laboratory of Neuropsychiatry, Department of Clinical and Behavioral Neurology, IRCCS Santa Lucia Foundation
Elizabeth D. Ballard - Experimental Therapeutics and Pathophysiology Branch, National Institute of Mental Health
Nerisa Banaj - Laboratory of Neuropsychiatry, Department of Clinical and Behavioral Neurology, IRCCS Santa Lucia Foundation
Zeynep Başgöze - University of Minnesota
Sophie Bellow - University of Cambridge
Francesco Benedetti - Università Vita-Salute San Raffaele
Irene Bollettini - Università Vita-Salute San Raffaele
Katharina Brosch - Department of Psychiatry and Psychotherapy and CMBB, University of Marburg
Erick J. Canales-Rodríguez - Signal Processing Laboratory (LTS5), EPFL
Emily K. Clarke-Rubright - Duke University School of Medicine
Lejla Colic - Center for Intervention and Research on adaptive and maladaptive brain Circuits underlying mental health (CIRC)
Colm G. Connolly - Florida State University
Philippe Courtet - Inserm
Kathryn R. Cullen - University of Minnesota
Udo Dannlowski - University of Münster
Maria R. Dauvermann - King's College London
Christopher G. Davey - The University of Melbourne
Jeremy Deverdun - Institut d’Imagerie Fonctionnelle Humaine, I2FH, Montpellier University Hospital Center, Gui de Chauliac Hospital, University of Montpellier
Katharina Dohm - University of Münster
Tracy Erwin-Grabner - Department of Psychiatry and Psychotherapy, University Medical Center Goettingen
Negar Fani - Emory University School of Medicine
Lydia Fortea - Instituto de Neurociencias
Paola Fuentes-Claramonte - CIBERSAM
Ali Saffet Gonul - Department of Psychiatry and Behavioral Sciences, School of Medicine, Mercer University Macon
Ian H. Gotlib - Stanford University
Dominik Grotegerd - University of Münster
Mathew A. Harris - University of Edinburgh
Ben J. Harrison - The University of Melbourne
Courtney C. Haswell - Duke University School of Medicine
Emma L. Hawkins - University of Edinburgh
Dawson Hill - University of Minnesota
Yoshiyuki Hirano - Hamamatsu University School of Medicine
Tiffany C. Ho - Department of Psychiatry and Behavioral Sciences and Weill Institute for Neurosciences, University of California
Fabrice Jollant - Universitätsklinikum Jena
Tanja Jovanovic - Wayne State University
Tilo Kircher - Department of Psychiatry and Psychotherapy and CMBB, University of Marburg
Bonnie Klimes-Dougan - University of Minnesota
Emmanuelle le Bars - Department of Neuroradiology, Montpellier University Hospital, Gui de Chauliac Hospital
Christine Lochner - Stellenbosch University
Andrew M. McIntosh - University of Edinburgh
Susanne Meinert - University of Münster
Yara Mekawi - Emory University School of Medicine
Elisa Melloni - Università Vita-Salute San Raffaele
Philip Mitchell - UNSW Sydney
Rajendra A. Morey - Duke University School of Medicine
Akiko Nakagawa - Hamamatsu University School of Medicine
Igor Nenadić - Department of Psychiatry and Psychotherapy and CMBB, University of Marburg
Emilie Olié - Inserm
Fabricio Pereira - MIPA, University of Nîmes
Rachel D. Phillips - Duke University School of Medicine
Fabrizio Piras - Laboratory of Neuropsychiatry, Department of Clinical and Behavioral Neurology, IRCCS Santa Lucia Foundation
Sara Poletti - Università Vita-Salute San Raffaele
Edith Pomarol-Clotet - CIBERSAM
Joaquim Radua - Centre for Psychiatric Research and Education, Department of Clinical Neuroscience, Karolinska Institutet
Kerry J. Ressler - Harvard Medical School
Gloria Roberts - UNSW Sydney
Elena Rodriguez-Cano - Benito Menni CASM
Matthew D. Sacchet - Harvard Medical School
Raymond Salvador - CIBERSAM
Anca-Larisa Sandu - Aberdeen Biomedical Imaging Centre, Institute of Medical Sciences, University of Aberdeen
Eiji Shimizu - Hamamatsu University School of Medicine
Aditya Singh - Department of Psychiatry and Psychotherapy, University Medical Center Goettingen
Gianfranco Spalletta - Baylor College of Medicine
J. Douglas Steele - University of Dundee
Dan J. Stein - SAMRC Unit on Risk & Resilience in Mental Disorders, Dept of Psychiatry & Neuroscience Institute, University of Cape Town
Frederike Stein - Department of Psychiatry and Psychotherapy and CMBB, University of Marburg
Jennifer S. Stevens - Emory University School of Medicine
Giana I. Teresi - University of Pittsburgh
Aslihan Uyar-Demir - Ege University
Nic J. van der Wee - ResearchTheme Neuroscience and Leiden Institute for Brain and Cognition, Leiden University Medical Center
Steven J. van der Werff - Leiden University Medical Center
Sanne J.H. van Rooij - Emory University School of Medicine
Daniela Vecchio - Laboratory of Neuropsychiatry, Department of Clinical and Behavioral Neurology, IRCCS Santa Lucia Foundation
Norma Verdolini - Hospital Clinic, Institute of Neuroscience, University of Barcelona, IDIBAPS, CIBERSAM
Eduard Vieta - Hospital Clinic, Institute of Neuroscience, University of Barcelona, IDIBAPS, CIBERSAM
Gordon D. Waiter - University of Aberdeen
Heather Whalley - University of Edinburgh
Sarah L. Whittle - The University of Melbourne
Tony T. Yang - University of California, San Francisco
Carlos A. Zarate - Experimental Therapeutics and Pathophysiology Branch, National Institute of Mental Health
Paul M. Thompson - Imaging Genetics Center, Mark & Mary Stevens Neuroimaging & Informatics Institute, Keck School of Medicine, University of Southern California
Neda Jahanshad - Imaging Genetics Center, Mark & Mary Stevens Neuroimaging & Informatics Institute, Keck School of Medicine, University of Southern California
Anne-Laura van Harmelen - Social Security and Resilience Programme, Education and Child Studies, Leiden University
Hilary P. Blumberg - Yale School of Medicine
Lianne Schmaal - The University of Melbourne
Miguel E. Rentería - The University of Queensland
Détails de publication: medRxiv
Éditeur: Cold Spring Harbor Laboratory Press
Édition: 1.1
Nombre de pages: 22
Identifiants: 99139455809311
Unité académique: Institut de Génomique Fonctionnelle - IGF
Langue: English; Japanese
Type de ressource: Preprint