Abstract
The invention relates to a method of prepn. of arylamines and in particular a method of prepn. of aniline and the anilines substituted on the arom. nucleus, starting from ammonia and compds. of formula I, under mild conditions, which could be easily carried out on industrial scale, with good selectivities and yields, in the presence of a catalytic complex of copper. Compds. of formula I wherein E is mono- or polycyclic arom. or heterocyclic system or a part of it; R is a ring substituent, n is no. of substituents; Y is a leaving group, such as halogen or sulfonic acid ester of formula -OSO2R1 (R1 is C1-4 linear or ramified alkyl, Ph, tolyl or CF3), can be used as starting material. Example compd. 1-aminonaphthalene (II) was prepd. by amination of 1-iodonaphthalene with aq. ammonia catalyzed by copper/acetylacetonate complex.