α,β-D-CNA preorganization of unpaired loop moiety stabilizes DNA hairpin

Christelle Dupouy; Pierre Millard; Arnaud Boissonnet; Jean-Marc Escudier

doi:10.1039/c0cc00244e

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α,β-D-CNA preorganization of unpaired loop moiety stabilizes DNA hairpin

Journal article

Peer reviewed

α,β-D-CNA preorganization of unpaired loop moiety stabilizes DNA hairpin

Christelle Dupouy, Pierre Millard, Arnaud Boissonnet and Jean-Marc Escudier

Chemical Communications, Vol.46(28)

2010

DOI: https://doi.org/10.1039/c0cc00244e

PMID: 20539885

Abstract

DNA hairpin structures can be stabilized by introduction of constraint on the sugar phosphate backbone within the unpaired loop moiety by means of dinucleotides locked with an alpha torsion angle in gauche(+) configuration.

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Title: α,β-D-CNA preorganization of unpaired loop moiety stabilizes DNA hairpin
Creators - without role: Christelle Dupouy - Université de Montpellier, Institut des Biomolécules Max Mousseron - IBMM
Pierre Millard - Université Toulouse III - Paul Sabatier
Arnaud Boissonnet - Université Toulouse III - Paul Sabatier
Jean-Marc Escudier - Molécules d'Intérêt Biologique
Publication Details: Chemical Communications, Vol.46(28)
Identifiers: 9935296109311
Academic Unit: Institut des Biomolécules Max Mousseron - IBMM
Language: English
Resource Type: Journal article
Local Fields: hal-02131862