Venous Thromboembolism Risk and Prophylaxis in the Acute Care Hospital Setting (ENDORSE Survey) Findings in Surgical Patients

Ajay K. Kakkar; Alexander T. Cohen; Victor F. Tapson; Jean-Francois Bergmann; Samuel Goldhaber; Bruno Deslandes; Wei Huang; Frederick A. Anderson; Lyes Cherfi; Dehbia Ammour; Cherif Bentakouk; Razika Bourenane; Nadia Grainat; Abderahmane Maarouf; Abdelhak Sissaoui; Alexander Gallus; Venkatraman Ayyar; Denis Crimmins; Eng Gan; Simon McRae; Michael Seldon; Bhuwan Singh; F. M. Siddiqui; Kaniz Moula; Taimor Nawaz; Khwaja Nazimuddin; Saiyeedur Rahman; Shyamal Sarker; Ana Rocha; Carlos Brandao; Jose Costa; Alex Macedo; Roberto Marino; Paulo Menezes; Wille Oigman; Marcelo Paiva; Joao Pantoja; Edgar Schramm; Liane Tandeitnik; Jorge Timi; Haralambi Benov; Stefan Dimitrov Borisov; Anton Lalov; Boyko Mirazchijski; Arman Postadziyan; Krassimir Sokolov; Evgenii Statelov; Chavdar Stefanov; Antoaneta Stoykova; Sheri Tadzher; Radostin Todorov; Rodolfo Dennis; Freddy Rafael Mendez Duran; Alfredo Posada; Hector Restrepo; Jairo Roa; Juan Villadiego; Jaroslav Maly; Tomas Brabec; Jaromir Gumulec; Roman Jochymek; Ivana Kellnerova; Jan Kvasnicka; Miroslav Penka; Jindra Skarkova; Premysl Slezak; Patrik Vit; Petr Vojtisek; Hadi Gobran; Alaa Mahmaud Aba El Rahman; Alaa El Haddad; George Sobhy Gorgy; Mounir Rizk-Allah; Sherif Sholkamy; Jean Francois Bergmann; Marid Abinader; Falah Abou Khoudir; Jean-Francois Boyer; Natacha Brun; Bernard Canet; Catherine Collard; Christophe Cordier; Claire Durroux; Joseph Emmerich; Patrick Friocourt; Patrick Genay; Florent Ibouanga; Abdelrhani Moumen; Pierre Philippe; Pierre Planchon; Yves Protin; Isabelle Quere; Marie-Jeanne Rizcallah; Rainer Zotz; Kristina Bensch; Klaus Bensmann; Axl Dropmann; Dieter Gerold; Andreas Gussmann; Bernd Kortmann; ENDORSE Investigators

doi:10.1097/SLA.0b013e3181c0e58f

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Venous Thromboembolism Risk and Prophylaxis in the Acute Care Hospital Setting (ENDORSE Survey) Findings in Surgical Patients

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Venous Thromboembolism Risk and Prophylaxis in the Acute Care Hospital Setting (ENDORSE Survey) Findings in Surgical Patients

Ajay K. Kakkar, Alexander T. Cohen, Victor F. Tapson, Jean-Francois Bergmann, Samuel Goldhaber, Bruno Deslandes, Wei Huang, Frederick A. Anderson, Lyes Cherfi, Dehbia Ammour, …

Annals of surgery, Vol.251(2), pp.330-338

01/02/2010

DOI: https://doi.org/10.1097/SLA.0b013e3181c0e58f

PMID: 20054273

Résumé

Life Sciences & Biomedicine

Science & Technology

Surgery

Objective: To evaluate venous thromboembolism (VTE) risk in patients who underwent a major operation, including the use of, and factors influencing, American College of Chest Physicians-recommended types of VTE prophylaxis. Summary Background Data: The Epidemiologic International Day for the Evaluation of Patients at Risk for Venous Thromboembolism in the Acute Hospital Care Setting (ENDORSE) survey, conducted in 358 hospitals in 3 2 countries, reported that globally, more than 40% of at-risk patients do not receive VTE prophylaxis. Limited data are available regarding VTE prophylaxis practices according to surgery type and patient characteristics. Methods: Patients aged >= 18 years undergoing major surgery were included in this prespecified subanalysis. VTE risk and use of prophylaxis were determined from hospital medical records according to the 2004 American College of Chest Physicians guidelines. Multivariable analyses were performed to identify factors associated with VTE prophylaxis use. Results: Of the 18,461 patients in ENDORSE who had undergone major surgery, 17,084 (92.5%) were at-risk for VTE and 10,638 (62,3%) received prophylaxis. Use of prophylaxis varied according to major surgery type from 86.0% for orthopedic surgery to 53.8% in urologic/gynecologic and 53.6% in other procedures. Major orthopedic surgery was most strongly associated with prophylaxis use (hip replacement: odds ratio 6.2, 95% confidence interval [CI] 5.0-7.6; knee replacement: odds ratio 5.9, 95% CI 4.6-7.8). Conclusions: The majority of surgical patients are at high-risk for VTE Despite long-standing recognition of the high-risk for VTE in surgical patients, thromboprophylaxis remains underutilized.

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Titre: Venous Thromboembolism Risk and Prophylaxis in the Acute Care Hospital Setting (ENDORSE Survey) Findings in Surgical Patients
Créateurs - sans rôle: Ajay K. Kakkar - Barts & London Queen Marys Sch Med & Dent, London SW3 6LR, England
Alexander T. Cohen - Kings Coll Hosp London, London, England
Victor F. Tapson - Duke Univ, Med Ctr, Durham, NC USA
Jean-Francois Bergmann - Univ Paris 07, Hop Lariboisiere, Paris, France
Samuel Goldhaber - Harvard University
Bruno Deslandes - Sanofi Aventis, Paris, France
Wei Huang - Univ Massachusetts, Sch Med, Dept Surg, Ctr Outcomes Res, Worcester, MA USA
Frederick A. Anderson - Univ Massachusetts, Sch Med, Dept Surg, Ctr Outcomes Res, Worcester, MA USA
Lyes Cherfi - CHU Nedir Mohamed, Tizi Ouzou, Algeria
Dehbia Ammour
Cherif Bentakouk - CHU Annaba, Annaba, Algeria
Razika Bourenane - Sect Sanit Guelma, Guelma, Algeria
Nadia Grainat - Benflis Touhami Hosp, Batna, Algeria
Abderahmane Maarouf - Chu Bab El Oued, Algiers, Algeria
Abdelhak Sissaoui - Salim Zmirli Hosp, Algiers, Algeria
Alexander Gallus - Flinders Private Hosp, Bedford Pk, SA, Australia
Venkatraman Ayyar - Sir Charles Gairdner Hosp, Perth, WA, Australia
Denis Crimmins - Gosford Hosp, E Gosford, NSW, Australia
Eng Gan - Monash Med Ctr, Clayton, Vic 3168, Australia
Simon McRae - Queen Elizabeth Hosp, Woodville, SA 5011, Australia
Michael Seldon - John Hunter Hosp, Waratah, NSW, Australia
Bhuwan Singh - Launceston Gen Hosp, Launceston, Tas, Australia
F. M. Siddiqui
Kaniz Moula - Holy Family Red Crescent Med Coll Hosp, Dhaka, Bangladesh
Taimor Nawaz - Bangladesh Med Coll Hosp, Dhaka, Bangladesh
Khwaja Nazimuddin - BIRDEM, Dhaka, Bangladesh
Saiyeedur Rahman - Mymensingh Med Coll Hosp, Mymensingh, Bangladesh
Shyamal Sarker - Dhaka Med Coll Hosp, Dhaka, Bangladesh
Ana Rocha - Hosp Univ Prof Edgard Santos, Salvador, BA, Brazil
Carlos Brandao - Hosp Univ Gaffree & Guinle, Rio De Janeiro, RJ, Brazil
Jose Costa - Conjunto Hosp Sorocaba, Sao Paulo, Brazil
Alex Macedo - Santa Casa De Santos, Sao Paulo, Brazil
Roberto Marino - Madre Teresa, Belo Horizonte, MG, Brazil
Paulo Menezes - Hosp Santa Izabel, Salvador, BA, Brazil
Wille Oigman - Hosp Univ Pedro Ernesto, Rio De Janeiro, Brazil
Marcelo Paiva - Hosp 9 Julho, Sao Paulo, Brazil
Joao Pantoja - Hosp Copador, Rio De Janeiro, RJ, Brazil
Edgar Schramm - Sao Francisco de Paula, Pelotas, RS, Brazil
Liane Tandeitnik - Hosp Agamenon Magalhaes, Recife, PE, Brazil
Jorge Timi - UFPR, Hosp Clin, Curitiba, Parana, Brazil
Haralambi Benov - MHAT Dr StTcherkezov, Veliko Tarnovo, Bulgaria
Stefan Dimitrov Borisov - MHATEM Dr Atanas Dafovski, Kardrzhali, Bulgaria
Anton Lalov - MBAL Dr Braton Shukerov AD Smoljan, Smoljan, Bulgaria
Boyko Mirazchijski - MHATEM Bourgas, Burgas, Bulgaria
Arman Postadziyan - Univ Hosp St Anne, Sofia, Bulgaria
Krassimir Sokolov - Gen Hosp Pazardzhik, Pazardzhik, Bulgaria
Evgenii Statelov - MBAL Plovdiv AD, Plovdiv, Bulgaria
Chavdar Stefanov - Univ Hosp St George, Plovdiv, Bulgaria
Antoaneta Stoykova - MHATEM Tota Venkova, Gabrovo, Bulgaria
Sheri Tadzher - MHATEM Pirogov, Sofia, Bulgaria
Radostin Todorov - MHATEM Dr Ivan Seliminski, Sliven, Bulgaria
Rodolfo Dennis
Freddy Rafael Mendez Duran - Clin Soma, Medellin, Antioquia, Colombia
Alfredo Posada - Clin Villapilar, Manizales, Colombia
Hector Restrepo - Fdn Cardioinfantil, Bogota, Cundinamarca, Colombia
Jairo Roa - Hosp Univ Fdn Santa Fe Bogota, Bogota, DC, Colombia
Juan Villadiego - Clin Rafael Uribe Uribe, Cali, Colombia
Jaroslav Maly
Tomas Brabec - Mil Hosp BRNO, Brno, Czech Republic
Jaromir Gumulec - Nemocnice Valasske Mezirici, Novy Jiojn, Czech Republic
Roman Jochymek - Nemocnice Trinec Po, Hradek, Czech Republic
Ivana Kellnerova - Nemocnice Svitavach, Svitavy, Czech Republic
Jan Kvasnicka - Gen Univ Hosp VFN, Prague 2, Czech Republic
Miroslav Penka - Fac Hosp BRNO, Brno, Czech Republic
Jindra Skarkova - HTO, Mestska Masarykova Nemocnice, Jilemnice, Czech Republic
Premysl Slezak - Sumperska Hosp, Sumperk, Czech Republic
Patrik Vit - Mestska Nemocnico Dvur Kralove ML RS, Dvur Kralove Labem, Czech Republic
Petr Vojtisek - Krajska Nemocnice Pardubice, Kardiol Oddeleni, Pardubice, Czech Republic
Hadi Gobran - Kasr E Eine Cairo Univ Hosp, Cairo, Egypt
Alaa Mahmaud Aba El Rahman
Alaa El Haddad - Natl Canc Inst, Cairo, Egypt
George Sobhy Gorgy - Dr Mohammed Al Shabrawishi Hosp, Giza, Egypt
Mounir Rizk-Allah - Alsalam Hosp, Cairo, Egypt
Sherif Sholkamy - Cairo Specialized Hosp, Cairo, Egypt
Jean Francois Bergmann
Marid Abinader - Clin Arc Ciel Olcomendy, Oloron Sainte Marie, France
Falah Abou Khoudir - Hop Henri Duffaut, Avignon, France
Jean-Francois Boyer - Clin St Privat, Beziers, France
Natacha Brun - Ctr Hosp Combarel, Rodex, France
Bernard Canet - Hop Langres, Langres, France
Catherine Collard - Ctr Hosp Luneville, Luneville, France
Christophe Cordier - Ctr Hosp Seclin, Seclin, France
Claire Durroux - Ctr Hosp Cassabel, Castelnaudary, France
Joseph Emmerich - Hop European George Pompidou, Paris, France
Patrick Friocourt - Ctr Hosp Blois, Blois, France
Patrick Genay - Ctr Hosp Dept, La Roche Sur Yon 9, France
Florent Ibouanga - Ctr Hosp Reg St Omer, St Omer, France
Abdelrhani Moumen - Ctr Hosp Nord Mayenne, Mayenne, France
Pierre Philippe - Chu Clermont Ferrand, Hotel Dieu, Clermont Ferrand, France
Pierre Planchon - Hop Hotel Dieu, Nantes, France
Yves Protin - Ctr Hosp Sedan, Sedan, France
Isabelle Quere - St Eloi Hop, Montpellier, France
Marie-Jeanne Rizcallah - Ctr Hosp Cornouaille, Quimper, France
Rainer Zotz
Kristina Bensch - Stadt Klinikum Magdeburg, Magdeburg, Germany
Klaus Bensmann - St Imgardis Krankenhaus, Viersen, Germany
Axl Dropmann - Chirurg Klin Seefeld, Seefeld, Germany
Dieter Gerold - DRK KH Diez, Diez, Germany
Andreas Gussmann - Humaine Klinikum Bad Saarow, Bad Saarow Pieskow, Germany
Bernd Kortmann - Ammerland Klin, Westerstede, Germany
ENDORSE Investigators
Détails de publication: Annals of surgery, Vol.251(2), pp.330-338
Éditeur: Lippincott Williams & Wilkins
Nombre de pages: 9
Note de subvention: sanofi-aventis (Paris, France); Sanofi-Aventis
Identifiants: 99139148009311
Unité académique: Institut Desbrest d Epidemiologie et de Sante Publique - IDESP
Langue: English
Type de ressource: Journal article