Utility of reassessment after neoadjuvant therapy and difficulties in interpretation

M.-A. Pierredon-Foulongne; S. Nougaret; F. Bibeau; P. Rouanet; E. Delhom; J. Lonjon; N. Ragu; J. Colleau; V. Schembri; B. Guiu; B. Gallix

doi:10.1016/j.diii.2014.03.010

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Utility of reassessment after neoadjuvant therapy and difficulties in interpretation

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Utility of reassessment after neoadjuvant therapy and difficulties in interpretation

M.-A. Pierredon-Foulongne, S. Nougaret, F. Bibeau, P. Rouanet, E. Delhom, J. Lonjon, N. Ragu, J. Colleau, V. Schembri, B. Guiu, …

Diagnostic and interventional imaging, Vol.95(5), pp.495-503

01/05/2014

DOI: https://doi.org/10.1016/j.diii.2014.03.010

PMID: 24767672

Résumé

Cancer

Neoadjuvant therapy

Rectum

Response

We describe the main tools for MR assessment of the response of rectal cancer tumors after chemotherapy, before surgery. In locally advanced cases of rectal and lower rectal cancer, MR is useful in allowing the treatment strategy to be adjusted, enabling conservative surgery to be performed if the patient responds well. The different types of response (fibrous, desmoplastic and colloid), their appearances and difficulties in MR interpretation are described. We describe the features and performance of MR after neoadjuvant therapy for T and N staging, assessment of circumferential resection margin and diffusion weighted imaging. Quantitative (change in tumor volume) and qualitative (grade of tumor response) MR assessment can distinguish good responders from poor responders.

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Détails

Titre: Utility of reassessment after neoadjuvant therapy and difficulties in interpretation
Créateurs - sans rôle: M.-A. Pierredon-Foulongne - Department of Medical Imaging, Saint-Eloi Hospital, Montpellier University Hospitals, 80, avenue Augustin-Fliche, 34295 Montpellier cedex 5, France
S. Nougaret - Department of Medical Imaging, Saint-Eloi Hospital, Montpellier University Hospitals, 80, avenue Augustin-Fliche, 34295 Montpellier cedex 5, France
F. Bibeau - Department of Pathological Anatomy, Montpellier Regional Cancer Institute, 208, avenue des Apothicaires, 34298 Montpellier cedex 5, France
P. Rouanet - Department of Surgery, Montpellier Regional Cancer Institute, 208, avenue des Apothicaires, 34298 Montpellier cedex 5, France
E. Delhom - Department of Medical Imaging, Saint-Eloi Hospital, Montpellier University Hospitals, 80, avenue Augustin-Fliche, 34295 Montpellier cedex 5, France
J. Lonjon - Department of Medical Imaging, Saint-Eloi Hospital, Montpellier University Hospitals, 80, avenue Augustin-Fliche, 34295 Montpellier cedex 5, France
N. Ragu - Department of Medical Imaging, Saint-Eloi Hospital, Montpellier University Hospitals, 80, avenue Augustin-Fliche, 34295 Montpellier cedex 5, France
J. Colleau - Department of Medical Imaging, Saint-Eloi Hospital, Montpellier University Hospitals, 80, avenue Augustin-Fliche, 34295 Montpellier cedex 5, France
V. Schembri - Department of Medical Imaging, Saint-Eloi Hospital, Montpellier University Hospitals, 80, avenue Augustin-Fliche, 34295 Montpellier cedex 5, France
B. Guiu - Department of Diagnostic and Interventional Radiology, Dijon University Hospitals, 1, boulevard Jeanne-d’Arc, 21079 Dijon, France
B. Gallix - Department of Medical Imaging, Saint-Eloi Hospital, Montpellier University Hospitals, 80, avenue Augustin-Fliche, 34295 Montpellier cedex 5, France
Détails de publication: Diagnostic and interventional imaging, Vol.95(5), pp.495-503
Éditeur: Elsevier Masson SAS
Nombre de pages: 9
Identifiants: 99149032309311
Unité académique: Recherche hors université
Langue: English
Type de ressource: Journal article