Abstract
Phenolic secondary metabolites are recognized as excellent antioxidants and are subject of numerous scientificstudies. The present study was aimed firstly, to quantify the phenolic constituents contained in the hydroacetoniccrude extract obtained from Gmelina arborea leaves by UPLC-MS/MS and secondly, to investigate in vitro itsanticancer potential against 6 cancerous cell lines. The quantitative analysis revealed a significant abundance inflavonoids (75.50%) and a presence of hydroxycinnamic acid derivatives (24.49%). The results of cytotoxicitysurvey clearly indicate that the hydroacetonic crude extract shows a good anticancer activity against C6 gliomacells.