Treatment of allergic rhinitis during and outside the pollen season using mobile technology. A MASK study

Annabelle Bédard; X. Basagaña; Josep María Anto; Judith Garcia-Aymerich; Philippe Devillier; Sylvie Arnavielhe; Anna Bedbrook; Gabrielle L. Onorato; Wienczyslawa Czarlewski; Ruth Brigid Murray; Rute Almeida; João Almeida Fonseca; J. Correia da Sousa; Elísio Costa; Mário A. Morais-Almeida; A. Todo-Bom; Lorenzo Cecchi; Giulia de Feo; Maddalena Illario; Enrica Menditto; Riccardo Monti; Cristiana Stellato; M. T. Ventura; Isabella Annesi-Maesano; Isabelle Bosse; Jean François M. Fontaine; Nhân Pham-Thi; Michel Thibaudon; Peter D. Schmid-Grendelmeier; François Spertini; N. Chavannes; Wytske Johanna Fokkens; Sietze Reitsma; Ruta Dubakiene; Regina Emuzyte; Violeta Kvedariene; Arũnas Valiulis; P. Kuna; Bolesław Samolinski; Ludger Klimek; Ralph Mösges; Oliver Pfaar; Sara Shamai; Regina Elisabeth Roller-Wirnsberger; Peter Valentin Tomazic; Dermot P. Ryan; Aziz Sheikh; Tari M.K. Haahtela; Sanna Katriina Toppila-Salmi; Erkka Juhani Valovirta; Victoria Cardona; Joaquim Mullol; Antonio Luís Valero; Michaël P. Makris; N. G. Papadopoulos; Emmanuel P. Prokopakis; Fotis Psarros; Claus Bachert; Peter William Hellings; Benoit Pugin; Carsten Bindslev-Jensen; Esben E. Eller; Inger Kull; Erik Melén; Magnus C. Wickman; Govert de Vries; Michiel van Eerd; Ioana O. Agache; Ignacio Javier Ansotegui; Sinthia Z. Bosnic-Anticevich; Álvaro Augusto Cruz; Thomas B. Casale; J. C. Ivancevich; Désirée E.S. Larenas-Linnemann; Mikhail Sofiev; Dana V. Wallace; Susan Waserman; Arzu Yorgancioglu; Daniel Laune; Jean J. Bousquet

doi:10.1186/s13601-020-00342-x

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Treatment of allergic rhinitis during and outside the pollen season using mobile technology. A MASK study

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Treatment of allergic rhinitis during and outside the pollen season using mobile technology. A MASK study

Annabelle Bédard, X. Basagaña, Josep María Anto, Judith Garcia-Aymerich, Philippe Devillier, Sylvie Arnavielhe, Anna Bedbrook, Gabrielle L. Onorato, Wienczyslawa Czarlewski, Ruth Brigid Murray, …

Clinical and Translational Allergy, Vol.10(1)

2020

DOI: https://doi.org/10.1186/s13601-020-00342-x

Abstract

Allergic rhinitis

Anti-histamines

Corticosteroids

ICT

MASK

Mobile health

Treatment

Background: The analysis of mobile health (mHealth) data has generated innovative insights into improving allergic rhinitis control, but additive information is needed. A cross-sectional real-world observational study was undertaken in 17 European countries during and outside the estimated pollen season. The aim was to collect novel information including the phenotypic characteristics of the users. Methods: The Allergy Diary–MASK-air–mobile phone app, freely available via Google Play and App, was used to collect the data of daily visual analogue scales (VASs) for overall allergic symptoms and medication use. Fluticasone Furoate (FF), Mometasone Furoate (MF), Azelastine Fluticasone Proprionate combination (MPAzeFlu) and eight oral H1-antihistamines were studied. Phenotypic characteristics were recorded at entry. The ARIA severity score was derived from entry data. This was an a priori planned analysis. Results: 9037 users filled in 70,286 days of VAS in 2016, 2017 and 2018. The ARIA severity score was lower outside than during the pollen season. Severity was similar for all treatment groups during the pollen season, and lower in the MPAzeFlu group outside the pollen season. Days with MPAzeFlu had lower VAS levels and a higher frequency of monotherapy than the other treatments during the season. Outside the season, days with MPAzeFlu also had a higher frequency of monotherapy. The number of reported days was significantly higher with MPAzeFlu during and outside the season than with MF, FF or oral H1-antihistamines. Conclusions: This study shows that the overall efficacy of treatments is similar during and outside the pollen season and indicates that medications are similarly effective during the year.

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Title: Treatment of allergic rhinitis during and outside the pollen season using mobile technology. A MASK study
Creators - without role: Annabelle Bédard - Barcelona Institute for Global Health
X. Basagaña - Barcelona Institute for Global Health
Josep María Anto - Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública
Judith Garcia-Aymerich - Barcelona Institute for Global Health
Philippe Devillier - Hôpital Foch
Sylvie Arnavielhe - KYomed INNOV [Montpellier]
Anna Bedbrook - Centre Hospitalier Universitaire de Montpellier
Gabrielle L. Onorato - Centre Hospitalier Universitaire de Montpellier
Wienczyslawa Czarlewski
Ruth Brigid Murray
Rute Almeida - Universidade do Porto
João Almeida Fonseca - Universidade do Porto
J. Correia da Sousa
Elísio Costa - Universidade do Porto
Mário A. Morais-Almeida - CUF Porto Hospital
A. Todo-Bom - Hospitais da Universidade de Coimbra
Lorenzo Cecchi - Azienda Usl Toscana Centro
Giulia de Feo - University of Salerno
Maddalena Illario - Federico II University Hospital
Enrica Menditto - Federico II University Hospital
Riccardo Monti
Cristiana Stellato - University of Bari Aldo Moro
M. T. Ventura - Sorbonne Université
Isabella Annesi-Maesano - Institut Pierre Louis d‘Épidémiologie et de Santé Publique
Isabelle Bosse - Roche
Jean François M. Fontaine - Fractionnation of AgroResources and Environment
Nhân Pham-Thi - École Polytechnique
Michel Thibaudon - Réseau National de Surveillance Aérobiologique
Peter D. Schmid-Grendelmeier - University Hospital of Zurich
François Spertini - University Hospital of Lausanne
N. Chavannes - Leiden University Medical Center
Wytske Johanna Fokkens - Amsterdam University Medical Centers
Sietze Reitsma - Amsterdam University Medical Centers
Ruta Dubakiene - Vilnius University
Regina Emuzyte - Vilnius University
Violeta Kvedariene - Vilnius University
Arũnas Valiulis - Vilnius University
P. Kuna - Medical University of Lodz
Bolesław Samolinski - Medical University of Warsaw
Ludger Klimek - Zentrum für Rhinologie und Allergologie
Ralph Mösges
Oliver Pfaar - Philipps University of Marburg
Sara Shamai - University of Cologne
Regina Elisabeth Roller-Wirnsberger - Medical University of Graz
Peter Valentin Tomazic - Medical University of Graz
Dermot P. Ryan - University of Edinburgh
Aziz Sheikh - University of Edinburgh
Tari M.K. Haahtela
Sanna Katriina Toppila-Salmi - Helsinki University Hospital
Erkka Juhani Valovirta - University of Turku
Victoria Cardona
Joaquim Mullol - Hospital Clínic de Barcelona
Antonio Luís Valero - Universitat de Barcelona
Michaël P. Makris
N. G. Papadopoulos - Royal Manchester Children's Hospital
Emmanuel P. Prokopakis - University of Crete
Fotis Psarros - Athens Naval & Veterans Hospital
Claus Bachert - Ghent University Hospital
Peter William Hellings - University of Amsterdam
Benoit Pugin
Carsten Bindslev-Jensen - Odense University Hospital
Esben E. Eller - Odense University Hospital
Inger Kull - Thermo Fisher Scientific
Erik Melén - Sachs' Children and Youth Hospital
Magnus C. Wickman - Sachs' Children and Youth Hospital
Govert de Vries - Center for Clinical Research Dalarna
Michiel van Eerd - Center for Clinical Research Dalarna
Ioana O. Agache
Ignacio Javier Ansotegui - Transylvania University of Brașov
Sinthia Z. Bosnic-Anticevich - Hospital Quirónsalud Barcelona
Álvaro Augusto Cruz - Universidade Federal da Bahia
Thomas B. Casale - University of South Florida
J. C. Ivancevich
Désirée E.S. Larenas-Linnemann
Mikhail Sofiev - Finnish Meteorological Institute
Dana V. Wallace - Nova Southeastern University
Susan Waserman - McMaster University
Arzu Yorgancioglu
Daniel Laune - KYomed INNOV [Montpellier]
Jean J. Bousquet - Centre Hospitalier Universitaire de Montpellier
Publication Details: Clinical and Translational Allergy, Vol.10(1)
Identifiers: 9945780209311
Academic Unit: Université de Montpellier
Language: English
Resource Type: Journal article
Local Fields: hal-03109218