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Thiocyanation of N,N-Dialkylhydrazonoyl Bromides: An Entry to Sulfur-Containing 1,2,4-Triazole Derivatives
Article de revue   Avec comité de lecture

Thiocyanation of N,N-Dialkylhydrazonoyl Bromides: An Entry to Sulfur-Containing 1,2,4-Triazole Derivatives

Alexis Prieto, Alexandre Uzel, Didier Bouyssi et Nuno Monteiro
European journal of organic chemistry, Vol.2017(28), pp.4201-4204
02/08/2017

Résumé

Chemistry Chemistry, Organic Physical Sciences Science & Technology
A simple and practical one-pot protocol involving sequential C-H bromination and thiocyanation of readily available aldehyde-derived N,N-dialkylhydrazones has been established for the synthesis of 5-thioxo-1,2,4-triazolium inner salts. Application of the method toward the synthesis of value-added 3-sulfanyl-1,2,4-triazoles through NS alkyl group transfer has also been demonstrated.

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