Résumé
The study of the early steps of HIV-1 infection is necessary to understand how the virus interacts with the cellular machinery to usurp the functions it requires for its replication. Our understanding in this field is critical for the establishment of new antiviral strategies and the development of gene transfer vectors derived from HIV-1 whose early steps are identical to those of HIV-1. This review aims to present our current understanding of the first part of the HIV-1 replication cycle, from its entry into the cell to its integration in the host cell chromatin.