The coffee genome provides insight into the convergent evolution of caffeine biosynthesis

France Denoeud; Lorenzo Carretero-Paulet; Alexis Dereeper; Gaëtan Droc; Romain Guyot; Marco Pietrella; Chunfang Zheng; Adriana A. Alberti; François Anthony; Giuseppe Aprea; Jean-Marc Aury; Pascal Bento; Maria Bernard; Stephanie Bocs; Claudine Campa; Alberto Cenci; Marie-Christine Combes; Dominique Crouzillat; Corinne da Silva; Loretta Daddiego; Fabien de Bellis; Stéphane Dussert; Olivier Garsmeur; Thomas Gayraud; Valentin Guignon; Katharina Jahn; Véronique Jamilloux; Thierry Joet; Karine Labadie; Tianying Lan; Julie Leclercq; Maud Lepelley; Thierry Leroy; Lei-Ting Li; Pablo Librado; Loredana Lopez; Adriana Muñoz; Benjamin Noel; Alberto Pallavicini; Gaetano Perrotta; Valérie Poncet; David Pot; - Priyono; Michel Rigoreau; Mathieu Rouard; Julio Rozas; Christine Tranchant-Dubreuil; Robert Vanburen; Qiong Zhang; Alan C Andrade; Xavier Argout; Benoit Bertrand; Alexandre de Kochko; Giorgio Graziosi; Robert J Henry; - Jayarama; Ray Ming; Chifumi Nagai; Steve Rounsley; David Sankoff; Giovanni Giuliano; Victor A Albert; Patrick Wincker; Philippe Lashermes

doi:10.1126/science.1255274

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The coffee genome provides insight into the convergent evolution of caffeine biosynthesis

Journal article

Peer reviewed

The coffee genome provides insight into the convergent evolution of caffeine biosynthesis

France Denoeud, Lorenzo Carretero-Paulet, Alexis Dereeper, Gaëtan Droc, Romain Guyot, Marco Pietrella, Chunfang Zheng, Adriana A. Alberti, François Anthony, Giuseppe Aprea, …

Science, Vol.345(6201), pp.1181-1184

05/09/2014

DOI: https://doi.org/10.1126/science.1255274

PMID: 25190796

Abstract

coffea

genome

genetics

evolution

caffeine

biosynthèse

Coffee is a valuable beverage crop due to its characteristic flavor, aroma, and the stimulating effects of caffeine. We generated a high-quality draft genome of the species Coffea canephora, which displays a conserved chromosomal gene order among asterid angiosperms. Although it shows no sign of the whole-genome triplication identified in Solanaceae species such as tomato, the genome includes several species-specific gene family expansions, among them N-methyltransferases (NMTs) involved in caffeine production, defense-related genes, and alkaloid and flavonoid enzymes involved in secondary compound synthesis. Comparative analyses of caffeine NMTs demonstrate that these genes expanded through sequential tandem duplications independently of genes from cacao and tea, suggesting that caffeine in eudicots is of polyphyletic origin.

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Title: The coffee genome provides insight into the convergent evolution of caffeine biosynthesis
Creators - without role: France Denoeud - Laboratoire de Bioinformatique pour la Génomique et la Biodiversité
Lorenzo Carretero-Paulet - University at Buffalo, State University of New York
Alexis Dereeper - Université de Montpellier, Plant Health Institute of Montpellier - PHIM
Gaëtan Droc - Centre de Coopération Internationale en Recherche Agronomique pour le Développement
Romain Guyot - Université de Montpellier, Diversité, Adaptation et Développement des plantes - DIADE
Marco Pietrella - National Agency for New Technologies, Energy and Sustainable Economic Development
Chunfang Zheng - University of Ottawa
Adriana A. Alberti - Genoscope
François Anthony - Université de Montpellier, Plant Health Institute of Montpellier - PHIM
Giuseppe Aprea - National Agency for New Technologies, Energy and Sustainable Economic Development
Jean-Marc Aury - Laboratoire de Bioinformatique pour la Génomique et la Biodiversité
Pascal Bento - Genoscope
Maria Bernard - Genoscope
Stephanie Bocs - Genetic Improvement and Adaptation of Mediterranean and Tropical Plants
Claudine Campa - Diversité, adaptation et développement des plantes
Alberto Cenci - Institut de Recherche pour le Développement
Marie-Christine Combes - Université de Montpellier, Plant Health Institute of Montpellier - PHIM
Dominique Crouzillat - Nestlé
Corinne da Silva - Genoscope
Loretta Daddiego - National Agency for New Technologies, Energy and Sustainable Economic Development
Fabien de Bellis - Genetic Improvement and Adaptation of Mediterranean and Tropical Plants
Stéphane Dussert - Diversité, adaptation et développement des plantes
Olivier Garsmeur - Genetic Improvement and Adaptation of Mediterranean and Tropical Plants
Thomas Gayraud - Université de Montpellier, Diversité, Adaptation et Développement des plantes - DIADE
Valentin Guignon - Agropolis International
Katharina Jahn - University of Ottawa
Véronique Jamilloux - Unité de Recherche Génomique Info
Thierry Joet - Université de Montpellier, Diversité, Adaptation et Développement des plantes - DIADE
Karine Labadie - Genoscope
Tianying Lan - Chongqing University of Science and Technology
Julie Leclercq - Genetic Improvement and Adaptation of Mediterranean and Tropical Plants
Maud Lepelley - Nestlé
Thierry Leroy - Genetic Improvement and Adaptation of Mediterranean and Tropical Plants
Lei-Ting Li - University of Illinois Urbana-Champaign
Pablo Librado - Universitat de Barcelona
Loredana Lopez - National Agency for New Technologies, Energy and Sustainable Economic Development
Adriana Muñoz - University of Maryland, College Park
Benjamin Noel - Genoscope
Alberto Pallavicini - University of Trieste
Gaetano Perrotta - ENEA Trisaia Research Centre
Valérie Poncet - Université de Montpellier, Diversité, Adaptation et Développement des plantes - DIADE
David Pot - Genetic Improvement and Adaptation of Mediterranean and Tropical Plants
- Priyono - Indonesian Coffee and Cocoa Research Institute
Michel Rigoreau - Nestlé
Mathieu Rouard - Agropolis International
Julio Rozas - Universitat de Barcelona
Christine Tranchant-Dubreuil - Université de Montpellier, Diversité, Adaptation et Développement des plantes - DIADE
Robert Vanburen - University of Illinois Urbana-Champaign
Qiong Zhang - University of Illinois Urbana-Champaign
Alan C Andrade - Brazilian Agricultural Research Corporation
Xavier Argout - Genetic Improvement and Adaptation of Mediterranean and Tropical Plants
Benoit Bertrand - Centre de Coopération Internationale en Recherche Agronomique pour le Développement
Alexandre de Kochko - Université de Montpellier, Diversité, Adaptation et Développement des plantes - DIADE
Giorgio Graziosi - University of Trieste
Robert J Henry - The University of Queensland
- Jayarama - The University of Queensland
Ray Ming - University of Illinois Urbana-Champaign
Chifumi Nagai - Hawaii Agriculture Research Center
Steve Rounsley - University of Arizona
David Sankoff - University of Ottawa
Giovanni Giuliano - National Agency for New Technologies, Energy and Sustainable Economic Development
Victor A Albert - University at Buffalo, State University of New York
Patrick Wincker - Genoscope
Philippe Lashermes - Université de Montpellier, Plant Health Institute of Montpellier - PHIM
Publication Details: Science, Vol.345(6201), pp.1181-1184
Grant note: Australian Research Council ; Natural Sciences and Engineering Research Council of Canada ; CNR-ENEA Agrifood Project A2 C44 L191 ; FINEP-Qualicafe ; NSF 0922742 0922545 ; College of Arts and Sciences, University at Buffalo ; SouthGreen Bioinformatics platform (UMR AGAP) ; CIRAD ; INCT-CAFE ; ANR-08-GENM-022-001 ; ANR-09-GENM-014-002
Identifiers: 99104503409311
Academic Unit: Diversité, Adaptation et Développement des plantes - DIADE; Plant Health Institute of Montpellier - PHIM
Language: English
Resource Type: Journal article
Local Fields: hal-02641562