The FANCM:p.Arg658 truncating variant is associated with risk of triple-negative breast cancer

Gisella Figlioli; Massimo Bogliolo; Irene Catucci; Laura Caleca; Sandra Viz Lasheras; Roser Pujol; Johanna Kiiski; Taru A Muranen; Daniel R Barnes; Joe Dennis; Kyriaki Michailidou; Manjeet K Bolla; Goska Leslie; Cora M Aalfs; Muriel A Adank; Julian Adlard; Simona Agata; Karen Cadoo; Bjarni A Agnarsson; Thomas Ahearn; Kristiina Aittomaki; Christine B Ambrosone; Lesley Andrews; Hoda Anton-Culver; Natalia N Antonenkova; Volker Arndt; Norbert Arnold; Kristan J Aronson; Banu K Arun; Ella Asseryanis; Bernd Auber; Paivi Auvinen; Jacopo Azzollini; Judith Balmana; Rosa B Barkardottir; Daniel Barrowdale; Julian Barwell; Laura E Beane Freeman; Charles Joly Beauparlant; Matthias W Beckmann; Sabine Behrens; Javier Benitez; Raanan Berger; Marina Bermisheva; Amie M Blanco; Carl Blomqvist; Natalia Bogdanova; Anders Bojesen; Stig E Bojesen; Bernardo Bonanni; Ake Borg; Angela F Brady; Hiltrud Brauch; Hermann Brenner; Thomas Bruening; Barbara Burwinkel; Saundra S Buys; Trinidad Caldes; Almuth Caliebe; Maria A Caligo; Daniele Campa; Ian G Campbell; Federico Canzian; Jose E Castelao; Jenny Chang-Claude; Stephen J Chanock; Kathleen BM Claes; Christine L Clarke; Anita Collavoli; Thomas A Conner; David G Cox; Cezary Cybulski; Kamila Czene; Mary B Daly; Miguel de la Hoya; Peter Devilee; Orland Diez; Yuan Chun Ding; Gillian S Dite; Nina Ditsch; Susan M Domchek; Cecilia M Dorfling; Isabel dos-Santos-Silva; Katarzyna Durda; Miriam Dwek; Diana M Eccles; Arif B Ekici; A Heather Eliassen; Carolina Ellberg; Mikael Eriksson; D Gareth Evans; Peter A Fasching; Jonine Figueroa; Henrik Flyger; William D Foulkes; Tara M Friebel; Eitan Friedman; Marike Gabrielson; Pragna Gaddam; Manuela Gago-Dominguez; Chi Gao; Susan M Gapstur; Judy Garber; Montserrat Garcia-Closas; Jose A Garcia-Saenz; Mia M Gaudet; Simon A Gayther; Graham G Giles; Gord Glendon; Andrew K Godwin; Mark S Goldberg; David E Goldgar; Pascal Guenel; Angelica M Gutierrez-Barrera; Lothar Haeberle; Christopher A Haiman; Niclas Hakansson; Per Hall; Ute Hamann; Patricia A Harrington; Alexander Hein; Jane Heyworth; Peter Hillemanns; Antoinette Hollestelle; John L Hopper; H Dean Hosgood; Anthony Howell; Chunling Hu; Peter J Hulick; David J Hunter; Evgeny N Imyanitov; Claudine Isaacs; Milena Jakimovska; Anna Jakubowska; Paul James; Ramunas Janavicius; Wolfgang Janni; Esther M John; Michael E Jones; Audrey Jung; Rudolf Kaaks; Beth Y Karlan; Elza Khusnutdinova; Cari M Kitahara; Irene Konstantopoulou; Stella Koutros; Peter Kraft; Diether Lambrechts; Conxi Lazaro; Loic Le Marchand; Jenny Lester; Fabienne Lesueur; Jenna Lilyquist; Jennifer T Loud; Karen H Lu; Robert N Luben; Jan Lubinski; Arto Mannermaa; Mehdi Manoochehri; Siranoush Manoukian; Sara Margolin; John WM Martens; Tabea Maurer; Dimitrios Mavroudis; Noura Mebirouk; Alfons Meindl; Usha Menon; Austin Miller; Marco Montagna; Katherine L Nathanson; Susan L Neuhausen; William G Newman; Tu Nguyen-Dumont; Finn Cilius Nielsen; Sarah Nielsen; Liene Nikitina-Zake; Kenneth Offit; Edith Olah; Olufunmilayo Olopade; Andrew F Olshan; Janet E Olson; Hakan Olsson; Ana Osorio; Laura Ottini; Bernard Peissel; Ana Peixoto; Julian Peto; Dijana Plaseska-Karanfilska; Timea Pocza; Nadege Presneau; Miquel Angel Pujana; Kevin Punie; Brigitte Rack; Johanna Rantala; Muhammad U Rashid; Rohini Rau-Murthy; Gad Rennert; Flavio Lejbkowicz; Valerie Rhenius; Atocha Romero; Matti A Rookus; Eric A Ross; Maria Rossing; Vilius Rudaitis; Matthias Ruebner; Emmanouil Saloustros; Kristin Sanden; Marta Santamarina; Maren T Scheuner; Rita K Schmutzler; Michael Schneider; Christopher Scott; Leigha Senter; Mitul Shah; Priyanka Sharma; Xiao-Ou Shu; Jacques Simard; Christian F Singer; Christof Sohn; Penny Soucy; Melissa C Southey; John J Spinelli; Linda Steele; Dominique Stoppa-Lyonnet; William J Tapper; Manuel R Teixeira; Mary Beth Terry; Mads Thomassen; Jennifer Thompson; Darcy L Thull; Marc Tischkowitz; Rob AEM Tollenaar; Diana Torres; Melissa A Troester; Therese Truong; Nadine Tung; Michael Untch; Celine M Vachon; Elizabeth J van Rensburg; Elke M van Veen; Ana Vega; Alessandra Viel; Barbara Wappenschmidt; Jeffrey N Weitzel; Camilla Wendt; Greet Wieme; Alicja Wolk; Xiaohong R Yang; Wei Zheng; Argyrios Ziogas; Kristin K Zorn; Alison M Dunning; Michael Lush; Qin Wang; Lesley McGuffog; Michael T Parsons; Paul DP Pharoah; Florentia Fostira; Amanda E Toland; Irene L Andrulis; Susan J Ramus; Anthony J Swerdlow; Mark H Greene; Wendy K Chung; Roger L Milne; Georgia Chenevix-Trench; Thilo Doerk; Marjanka K Schmidt; Douglas F Easton; Paolo Radice; Eric Hahnen; Antonis C Antoniou; Fergus J Couch; Heli Nevanlinna; Jordi Surralles; Paolo Peterlongo; Rosemary Balleine; Robert Baxter; Stephen Braye; Jane Carpenter; Jane Dahlstrom; John Forbes; C Soon Lee; Deborah Marsh; Adrienne Morey; Nirmala Pathmanathan; Rodney Scott; Peter Simpson; Allan Spigelman; Nicholas Wilcken; Desmond Yip; Nikolajs Zeps; Muriel Belotti; Ophelie Bertrand; Anne-Marie Birot; Bruno Buecher; Sandrine Caputo; Anais Dupre; Emmanuelle Fourme; Marion Gauthier-Villars; Lisa Golmard; Marine Le Mentec; Virginie Moncoutier; Antoine de Pauw; Claire Saule; Nadia Boutry-Kryza; Alain Calender; Sophie Giraud; Mlanie Leone; Brigitte Bressac-de-Paillerets; Olivier Caron; Marine Guillaud-Bataille; Yves-Jean Bignon; Nancy Uhrhammer; Valerie Bonadona; Christine Lasset; Pascaline Berthet; Laurent Castera; Dominique Vaur; Violaine Bourdon; Catherine Nogues; Tetsuro Noguchi; Cornel Popovici; Audrey Remenieras; Hagay Sobol; Isabelle Coupier; Pascal Pujol; Claude Adenis; Aurelie Dumont; Francoise Revillion; Daniele Muller; Emmanuelle Barouk-Simonet; Francoise Bonnet; Virginie Bubien; Michel Longy; Nicolas Sevenet; Laurence Gladieff; Rosine Guimbaud; Viviane Feillel; Christine Toulas; Helene Dreyfus; Christine Dominique Leroux; Magalie Peysselon; Christine Rebischung; Clementine Legrand; Amandine Baurand; Geoffrey Bertolone; Fanny Coron; Laurence Faivre; Caroline Jacquot; Sarab Lizard; Caroline Kientz; Marine Lebrun; Fabienne Prieur; Sandra Fert-Ferrer; Vronique Mari; Laurence Venat-Bouvet; Stephane Bezieau; Capucine Delnatte; Isabelle Mortemousque; Chrystelle Colas; Florence Coulet; Florent Soubrier; Mathilde Warcoin; Myriam Bronner; Johanna Sokolowska; Marie-Agnes Collonge-Rame; Alexandre Damette; Paul Gesta; Hakima Lallaoui; Jean Chiesa; Denise Molina-Gomes; Olivier Ingster; Sylvie Manouvrier-Hanu; Sophie Lejeune; Morteza Aghmesheh; Sian Greening; David Amor; Mike Gattas; Leon Botes; Michael Buckley; Michael Friedlander; Jessica Koehler; Bettina Meiser; Mona Saleh; Elizabeth Salisbury; Alison Trainer; Kathy Tucker; Yoland Antill; Alexander Dobrovic; Andrew Fellows; Stephen Fox; Marion Harris; Sophie Nightingale; Kelly Phillips; Joe Sambrook; Heather Thorne; Shane Armitage; Leanne Arnold; Rick Kefford; Judy Kirk; Edwina Rickard; Patti Bastick; Jonathan Beesley; Nick Hayward; Amanda Spurdle; Logan Walker; John Beilby; Christobel Saunders; Ian Bennett; Anneke Blackburn; Michael Bogwitz; Clara Gaff; Geoff Lindeman; Nick Pachter; Clare Scott; Adrienne Sexton; Jane Visvader; Jessica Taylor; Ingrid Winship; Meagan Brennan; Melissa Brown; Juliet French; Stacey Edwards; Matthew Burgess; Jo Burke; Briony Patterson; Phyllis Butow; Bronwyn Culling; Liz Caldon; David Callen; Deepa Chauhan; Maurice Eisenbruch; Louise Heiniger; Manisha Chauhan; Alice Christian; Joanne Dixon; Alexa Kidd; Paul Cohen; Alison Colley; Georgina Fenton; Ashley Crook; Rebecca Dickson; Michael Field; James Cui; Margaret Cummings; Sarah-Jane Dawson; Anna DeFazio; Martin Delatycki; Tracy Dudding; Ted Edkins; Gelareh Farshid; James Flanagan; Peter Fong; Laura Forrest; David Gallego-Ortega; Peter George; Grantley Gill; James Kollias; Eric Haan; Stewart Hart; Mark Jenkins; Clare Hunt; Sunil Lakhani; Lara Lipton; Liz Lobb; Graham Mann; Sue Anne McLachlan; Shona O'Connell; Sarah O'Sullivan; Ellen Pieper; Bridget Robinson; Jodi Saunus; Elizabeth Scott; Andrew Shelling; Rachael Williams; Mary Ann Young

doi:10.1038/s41523-019-0127-5

Retour

The FANCM:p.Arg658 truncating variant is associated with risk of triple-negative breast cancer

Article de revue

Avec comité de lecture

The FANCM:p.Arg658 truncating variant is associated with risk of triple-negative breast cancer

Gisella Figlioli, Massimo Bogliolo, Irene Catucci, Laura Caleca, Sandra Viz Lasheras, Roser Pujol, Johanna Kiiski, Taru A Muranen, Daniel R Barnes, Joe Dennis, …

npj Breast Cancer, Vol.5(1), 38

01/11/2019

DOI: https://doi.org/10.1038/s41523-019-0127-5

Résumé

C.5791C-GREATER-THAN-T

FANCONI-ANEMIA

GENE

Life Sciences & Biomedicine

MUTATIONS

Oncology

Science & Technology

Article Open Access Published: 01 November 2019 The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer Gisella Figlioli, Massimo Bogliolo, […]Paolo Peterlongo npj Breast Cancer volume 5, Article number: 38 (2019) Cite this article Article metrics 937 Accesses 22 Altmetric Metricsdetails Abstract Breast cancer is a common disease partially caused by genetic risk factors. Germline pathogenic variants in DNA repair genes BRCA1, BRCA2, PALB2, ATM, and CHEK2 are associated with breast cancer risk. FANCM, which encodes for a DNA translocase, has been proposed as a breast cancer predisposition gene, with greater effects for the ER-negative and triple-negative breast cancer (TNBC) subtypes. We tested the three recurrent protein-truncating variants FANCM:p.Arg658*, p.Gln1701*, and p.Arg1931* for association with breast cancer risk in 67,112 cases, 53,766 controls, and 26,662 carriers of pathogenic variants of BRCA1 or BRCA2. These three variants were also studied functionally by measuring survival and chromosome fragility in FANCM−/− patient-derived immortalized fibroblasts treated with diepoxybutane or olaparib. We observed that FANCM:p.Arg658* was associated with increased risk of ER-negative disease and TNBC (OR = 2.44, P = 0.034 and OR = 3.79; P = 0.009, respectively). In a country-restricted analysis, we confirmed the associations detected for FANCM:p.Arg658* and found that also FANCM:p.Arg1931* was associated with ER-negative breast cancer risk (OR = 1.96; P = 0.006). The functional results indicated that all three variants were deleterious affecting cell survival and chromosome stability with FANCM:p.Arg658* causing more severe phenotypes. In conclusion, we confirmed that the two rare FANCM deleterious variants p.Arg658* and p.Arg1931* are risk factors for ER-negative and TNBC subtypes. Overall our data suggest that the effect of truncating variants on breast cancer risk may depend on their position in the gene. Cell sensitivity to olaparib exposure, identifies a possible therapeutic option to treat FANCM-associated tumors.

Indicateurs

1 Consultations de la notice

See more details

Détails

Titre: The FANCM:p.Arg658 truncating variant is associated with risk of triple-negative breast cancer
Créateurs - sans rôle: Gisella Figlioli
Massimo Bogliolo
Irene Catucci
Laura Caleca
Sandra Viz Lasheras
Roser Pujol
Johanna Kiiski
Taru A Muranen
Daniel R Barnes
Joe Dennis
Kyriaki Michailidou
Manjeet K Bolla
Goska Leslie
Cora M Aalfs
Muriel A Adank
Julian Adlard
Simona Agata
Karen Cadoo
Bjarni A Agnarsson
Thomas Ahearn
Kristiina Aittomaki
Christine B Ambrosone
Lesley Andrews
Hoda Anton-Culver
Natalia N Antonenkova
Volker Arndt
Norbert Arnold
Kristan J Aronson
Banu K Arun
Ella Asseryanis
Bernd Auber
Paivi Auvinen
Jacopo Azzollini
Judith Balmana
Rosa B Barkardottir
Daniel Barrowdale
Julian Barwell
Laura E Beane Freeman
Charles Joly Beauparlant
Matthias W Beckmann
Sabine Behrens
Javier Benitez
Raanan Berger
Marina Bermisheva
Amie M Blanco
Carl Blomqvist
Natalia Bogdanova
Anders Bojesen
Stig E Bojesen
Bernardo Bonanni
Ake Borg
Angela F Brady
Hiltrud Brauch
Hermann Brenner
Thomas Bruening
Barbara Burwinkel
Saundra S Buys
Trinidad Caldes
Almuth Caliebe
Maria A Caligo
Daniele Campa
Ian G Campbell
Federico Canzian
Jose E Castelao
Jenny Chang-Claude
Stephen J Chanock
Kathleen BM Claes
Christine L Clarke
Anita Collavoli
Thomas A Conner
David G Cox
Cezary Cybulski
Kamila Czene
Mary B Daly
Miguel de la Hoya
Peter Devilee
Orland Diez
Yuan Chun Ding
Gillian S Dite
Nina Ditsch
Susan M Domchek
Cecilia M Dorfling
Isabel dos-Santos-Silva
Katarzyna Durda
Miriam Dwek
Diana M Eccles
Arif B Ekici
A Heather Eliassen
Carolina Ellberg
Mikael Eriksson
D Gareth Evans
Peter A Fasching
Jonine Figueroa
Henrik Flyger
William D Foulkes
Tara M Friebel
Eitan Friedman
Marike Gabrielson
Pragna Gaddam
Manuela Gago-Dominguez
Chi Gao
Susan M Gapstur
Judy Garber
Montserrat Garcia-Closas
Jose A Garcia-Saenz
Mia M Gaudet
Simon A Gayther
Graham G Giles
Gord Glendon
Andrew K Godwin
Mark S Goldberg
David E Goldgar
Pascal Guenel
Angelica M Gutierrez-Barrera
Lothar Haeberle
Christopher A Haiman
Niclas Hakansson
Per Hall
Ute Hamann
Patricia A Harrington
Alexander Hein
Jane Heyworth
Peter Hillemanns
Antoinette Hollestelle
John L Hopper
H Dean Hosgood
Anthony Howell
Chunling Hu
Peter J Hulick
David J Hunter
Evgeny N Imyanitov
Claudine Isaacs
Milena Jakimovska
Anna Jakubowska
Paul James
Ramunas Janavicius
Wolfgang Janni
Esther M John
Michael E Jones
Audrey Jung
Rudolf Kaaks
Beth Y Karlan
Elza Khusnutdinova
Cari M Kitahara
Irene Konstantopoulou
Stella Koutros
Peter Kraft
Diether Lambrechts
Conxi Lazaro
Loic Le Marchand
Jenny Lester
Fabienne Lesueur
Jenna Lilyquist
Jennifer T Loud
Karen H Lu
Robert N Luben
Jan Lubinski
Arto Mannermaa
Mehdi Manoochehri
Siranoush Manoukian
Sara Margolin
John WM Martens
Tabea Maurer
Dimitrios Mavroudis
Noura Mebirouk
Alfons Meindl
Usha Menon
Austin Miller
Marco Montagna
Katherine L Nathanson
Susan L Neuhausen
William G Newman
Tu Nguyen-Dumont
Finn Cilius Nielsen
Sarah Nielsen
Liene Nikitina-Zake
Kenneth Offit
Edith Olah
Olufunmilayo Olopade
Andrew F Olshan
Janet E Olson
Hakan Olsson
Ana Osorio
Laura Ottini
Bernard Peissel
Ana Peixoto
Julian Peto
Dijana Plaseska-Karanfilska
Timea Pocza
Nadege Presneau
Miquel Angel Pujana
Kevin Punie
Brigitte Rack
Johanna Rantala
Muhammad U Rashid
Rohini Rau-Murthy
Gad Rennert
Flavio Lejbkowicz
Valerie Rhenius
Atocha Romero
Matti A Rookus
Eric A Ross
Maria Rossing
Vilius Rudaitis
Matthias Ruebner
Emmanouil Saloustros
Kristin Sanden
Marta Santamarina
Maren T Scheuner
Rita K Schmutzler
Michael Schneider
Christopher Scott
Leigha Senter
Mitul Shah
Priyanka Sharma
Xiao-Ou Shu
Jacques Simard
Christian F Singer
Christof Sohn
Penny Soucy
Melissa C Southey
John J Spinelli
Linda Steele
Dominique Stoppa-Lyonnet
William J Tapper
Manuel R Teixeira
Mary Beth Terry
Mads Thomassen
Jennifer Thompson
Darcy L Thull
Marc Tischkowitz
Rob AEM Tollenaar
Diana Torres
Melissa A Troester
Therese Truong
Nadine Tung
Michael Untch
Celine M Vachon
Elizabeth J van Rensburg
Elke M van Veen
Ana Vega
Alessandra Viel
Barbara Wappenschmidt
Jeffrey N Weitzel
Camilla Wendt
Greet Wieme
Alicja Wolk
Xiaohong R Yang
Wei Zheng
Argyrios Ziogas
Kristin K Zorn
Alison M Dunning
Michael Lush
Qin Wang
Lesley McGuffog
Michael T Parsons
Paul DP Pharoah
Florentia Fostira
Amanda E Toland
Irene L Andrulis
Susan J Ramus
Anthony J Swerdlow
Mark H Greene
Wendy K Chung
Roger L Milne
Georgia Chenevix-Trench
Thilo Doerk
Marjanka K Schmidt
Douglas F Easton
Paolo Radice
Eric Hahnen
Antonis C Antoniou
Fergus J Couch
Heli Nevanlinna
Jordi Surralles
Paolo Peterlongo
Rosemary Balleine
Robert Baxter
Stephen Braye
Jane Carpenter
Jane Dahlstrom
John Forbes
C Soon Lee
Deborah Marsh
Adrienne Morey
Nirmala Pathmanathan
Rodney Scott
Peter Simpson
Allan Spigelman
Nicholas Wilcken
Desmond Yip
Nikolajs Zeps
Muriel Belotti
Ophelie Bertrand
Anne-Marie Birot
Bruno Buecher
Sandrine Caputo
Anais Dupre
Emmanuelle Fourme
Marion Gauthier-Villars
Lisa Golmard
Marine Le Mentec
Virginie Moncoutier
Antoine de Pauw
Claire Saule
Nadia Boutry-Kryza
Alain Calender
Sophie Giraud
Mlanie Leone
Brigitte Bressac-de-Paillerets
Olivier Caron
Marine Guillaud-Bataille
Yves-Jean Bignon
Nancy Uhrhammer
Valerie Bonadona
Christine Lasset
Pascaline Berthet
Laurent Castera
Dominique Vaur
Violaine Bourdon
Catherine Nogues
Tetsuro Noguchi
Cornel Popovici
Audrey Remenieras
Hagay Sobol
Isabelle Coupier
Pascal Pujol
Claude Adenis
Aurelie Dumont
Francoise Revillion
Daniele Muller
Emmanuelle Barouk-Simonet
Francoise Bonnet
Virginie Bubien
Michel Longy
Nicolas Sevenet
Laurence Gladieff
Rosine Guimbaud
Viviane Feillel
Christine Toulas
Helene Dreyfus
Christine Dominique Leroux
Magalie Peysselon
Christine Rebischung
Clementine Legrand
Amandine Baurand
Geoffrey Bertolone
Fanny Coron
Laurence Faivre
Caroline Jacquot
Sarab Lizard
Caroline Kientz
Marine Lebrun
Fabienne Prieur
Sandra Fert-Ferrer
Vronique Mari
Laurence Venat-Bouvet
Stephane Bezieau
Capucine Delnatte
Isabelle Mortemousque
Chrystelle Colas
Florence Coulet
Florent Soubrier
Mathilde Warcoin
Myriam Bronner
Johanna Sokolowska
Marie-Agnes Collonge-Rame
Alexandre Damette
Paul Gesta
Hakima Lallaoui
Jean Chiesa
Denise Molina-Gomes
Olivier Ingster
Sylvie Manouvrier-Hanu
Sophie Lejeune
Morteza Aghmesheh
Sian Greening
David Amor
Mike Gattas
Leon Botes
Michael Buckley
Michael Friedlander
Jessica Koehler
Bettina Meiser
Mona Saleh
Elizabeth Salisbury
Alison Trainer
Kathy Tucker
Yoland Antill
Alexander Dobrovic
Andrew Fellows
Stephen Fox
Marion Harris
Sophie Nightingale
Kelly Phillips
Joe Sambrook
Heather Thorne
Shane Armitage
Leanne Arnold
Rick Kefford
Judy Kirk
Edwina Rickard
Patti Bastick
Jonathan Beesley
Nick Hayward
Amanda Spurdle
Logan Walker
John Beilby
Christobel Saunders
Ian Bennett
Anneke Blackburn
Michael Bogwitz
Clara Gaff
Geoff Lindeman
Nick Pachter
Clare Scott
Adrienne Sexton
Jane Visvader
Jessica Taylor
Ingrid Winship
Meagan Brennan
Melissa Brown
Juliet French
Stacey Edwards
Matthew Burgess
Jo Burke
Briony Patterson
Phyllis Butow
Bronwyn Culling
Liz Caldon
David Callen
Deepa Chauhan
Maurice Eisenbruch
Louise Heiniger
Manisha Chauhan
Alice Christian
Joanne Dixon
Alexa Kidd
Paul Cohen
Alison Colley
Georgina Fenton
Ashley Crook
Rebecca Dickson
Michael Field
James Cui
Margaret Cummings
Sarah-Jane Dawson
Anna DeFazio
Martin Delatycki
Tracy Dudding
Ted Edkins
Gelareh Farshid
James Flanagan
Peter Fong
Laura Forrest
David Gallego-Ortega
Peter George
Grantley Gill
James Kollias
Eric Haan
Stewart Hart
Mark Jenkins
Clare Hunt
Sunil Lakhani
Lara Lipton
Liz Lobb
Graham Mann
Sue Anne McLachlan
Shona O'Connell
Sarah O'Sullivan
Ellen Pieper
Bridget Robinson
Jodi Saunus
Elizabeth Scott
Andrew Shelling
Rachael Williams
Mary Ann Young
Détails de publication: npj Breast Cancer, Vol.5(1), 38
Éditeur: Nature Research (part of Springer Nature)
Identifiants: 99159055809311
Unité académique: Maladies Infectieuses et Vecteurs : Ecologie, Génétique, Evolution et Contrôle - MIVEGEC; Institut des Biomolécules Max Mousseron - IBMM
Langue: English
Type de ressource: Journal article