The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors

Stephen Alexander; Arthur Christopoulos; Anthony Davenport; Eamonn Kelly; Alistair Mathie; John Peters; Emma Veale; Jane Armstrong; Elena Faccenda; Simon Harding; Jamie Davies; Maria Pia Abbracchio; George Abraham; Alexander Agoulnik; Wayne Alexander; Khaled Al-Hosaini; Magnus Bäck; Jillian Baker; Nicholas Barnes; Ross Bathgate; Jean‐martin Beaulieu; Annette Beck-Sickinger; Maik Behrens; Kenneth Bernstein; Bernhard Bettler; Nigel Birdsall; Victoria Blaho; Francois Boulay; Corinne Bousquet; Hans Bräuner-Osborne; Geoffrey Burnstock; Girolamo Caló; Justo Castaño; Kevin Catt; Stefania Ceruti; Paul Chazot; Nan Chiang; Bice Chini; Jerold Chun; Antonia Cianciulli; Olivier Civelli; Lucie Clapp; Réjean Couture; Helen Cox; Zsolt Csaba; Claes Dahlgren; Gordon Dent; Steven Douglas; Pascal Dournaud; Satoru Eguchi; Emanuel Escher; Edward Filardo; Tung Fong; Marta Fumagalli; Raul Gainetdinov; Michael Garelja; Marc de Gasparo; Craig Gerard; Marvin Gershengorn; Fernand Gobeil; Theodore Goodfriend; Cyril Goudet; Lukas Grätz; Karen Gregory; Andrew Gundlach; Jörg Hamann; Julien Hanson; Richard Hauger; Debbie Hay; Akos Heinemann; Deron Herr; Morley Hollenberg; Nicholas Holliday; Mastgugu Horiuchi; Daniel Hoyer; László Hunyady; Ahsan Husain; Adriaan Ijzerman; Tadashi Inagami; Kenneth Jacobson; Robert Jensen; Ralf Jockers; Deepa Jonnalagadda; Sadashiva Karnik; Klemens Kaupmann; Jacqueline Kemp; Charles Kennedy; Yasuyuki Kihara; Takio Kitazawa; Pawel Kozielewicz; Hans‐jürgen Kreienkamp; Jyrki Kukkonen; Tobias Langenhan; Dan Larhammar; Katie Leach; Davide Lecca; John Lee; Susan Leeman; Jérôme Leprince; Xaria Li; Stephen Lolait; Amelie Lupp; Robyn Macrae; Janet Maguire; Davide Malfacini; Jean Mazella; Craig Mcardle; Shlomo Melmed; Martin Michel; Laurence Miller; Vincenzo Mitolo; Bernard Mouillac; Christa Müller; Philip Murphy; Jean‐Louis Nahon; Tony Ngo; Xavier Norel; Duuamene Nyimanu; Anne‐marie O’carroll; Stefan Offermanns; Maria Antonietta Panaro; Marc Parmentier; Roger Pertwee; Jean‐philippe Pin; Eric Prossnitz; Mark Quinn; Rithwik Ramachandran; Manisha Ray; Rainer Reinscheid; Philippe Rondard; G. Enrico Rovati; Chiara Ruzza; Gareth Sanger; Torsten Schöneberg; Gunnar Schulte; Stefan Schulz; Deborah Segaloff; Charles Serhan; Khuraijam Dhanachandra Singh; Craig Smith; Leigh Stoddart; Yukihiko Sugimoto; Roger Summers; Valerie Tan; David Thal; Walter Thomas; Pieter Timmermans; Kalyan Tirupula; Lawrence Toll; Giovanni Tulipano; Hamiyet Unal; Thomas Unger; Celine Valant; Patrick Vanderheyden; David Vaudry; Hubert Vaudry; Jean‐pierre Vilardaga; Christopher Walker; Ji Ming Wang; Donald Ward; Hans‐jürgen Wester; Gary Willars; Tom Lloyd Williams; Trent Woodruff; Chengcan Yao; Richard Ye

doi:10.1111/bph.16177

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The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors

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The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors

Stephen Alexander, Arthur Christopoulos, Anthony Davenport, Eamonn Kelly, Alistair Mathie, John Peters, Emma Veale, Jane Armstrong, Elena Faccenda, Simon Harding, …

British Journal of Pharmacology, Vol.180(S2), pp.S23-S144

20/12/2023

DOI: https://doi.org/10.1111/bph.16177

PMID: 38123151

Abstract

The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and about 6000 interactions with about 3900 ligands. There is an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands ( https://www.guidetopharmacology.org ), which provides more detailed views of target and ligand properties. Although the Concise Guide constitutes almost 500 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point‐in‐time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/bph.16177 . G protein‐coupled receptors are one of the six major pharmacological targets into which the Guide is divided, with the others being: ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid‐2023, and supersedes data presented in the 2021/22, 2019/20, 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature and Standards Committee of the International Union of Basic and Clinical Pharmacology (NC‐IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.

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Title: The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors
Creators - without role: Stephen Alexander - University of Nottingham
Arthur Christopoulos - Monash University
Anthony Davenport - University of Cambridge
Eamonn Kelly - University of Bristol
Alistair Mathie - University of Suffolk
John Peters - Ninewells Hospital
Emma Veale - Medway School of Pharmacy
Jane Armstrong - University of Edinburgh
Elena Faccenda - University of Edinburgh
Simon Harding - University of Edinburgh
Jamie Davies - University of Edinburgh
Maria Pia Abbracchio - University of Milan
George Abraham - University College Dublin
Alexander Agoulnik - Florida International University
Wayne Alexander - Emory University
Khaled Al-Hosaini - King Saud University
Magnus Bäck - Karolinska University Hospital
Jillian Baker - University of Nottingham
Nicholas Barnes - University of Birmingham
Ross Bathgate - Florey Institute of Neuroscience and Mental Health
Jean‐martin Beaulieu - University of Toronto
Annette Beck-Sickinger - Leipzig University
Maik Behrens - Technical University of Munich
Kenneth Bernstein - Cedars-Sinai Medical Center
Bernhard Bettler - University of Basel
Nigel Birdsall - The Francis Crick Institute
Victoria Blaho - Discovery Institute
Francois Boulay - Université Grenoble Alpes
Corinne Bousquet - Inserm
Hans Bräuner-Osborne - University of Copenhagen
Geoffrey Burnstock - University College London
Girolamo Caló - University of Padua
Justo Castaño - University of Córdoba
Kevin Catt - National Institutes of Health [Bethesda, MD, USA]
Stefania Ceruti - University of Milan
Paul Chazot - Durham University
Nan Chiang - Boston University
Bice Chini - University of Milano-Bicocca
Jerold Chun - University of California, San Diego
Antonia Cianciulli - University of Bari Aldo Moro
Olivier Civelli - University of California, Irvine
Lucie Clapp - University College London
Réjean Couture - Université de Montréal
Helen Cox - King's College London
Zsolt Csaba - Inserm
Claes Dahlgren - University of Gothenburg
Gordon Dent - Keele University
Steven Douglas - University of Pennsylvania
Pascal Dournaud - Inserm
Satoru Eguchi - Temple University
Emanuel Escher - Université de Sherbrooke
Edward Filardo - University of Iowa
Tung Fong - LabCorp
Marta Fumagalli - University of Milan
Raul Gainetdinov - St Petersburg University
Michael Garelja - University of Otago
Marc de Gasparo - MG Consulting Co [Basel]
Craig Gerard - Boston University
Marvin Gershengorn - National Institutes of Health [Bethesda, MD, USA]
Fernand Gobeil - Université de Sherbrooke
Theodore Goodfriend - University of Wisconsin–Madison
Cyril Goudet - Université de Montpellier, Institut de Génomique Fonctionnelle - IGF
Lukas Grätz - Karolinska Institutet
Karen Gregory - Monash University
Andrew Gundlach - Florey Institute of Neuroscience and Mental Health
Jörg Hamann - Universiteit van Amsterdam
Julien Hanson - University of Liège
Richard Hauger - University of California, San Diego
Debbie Hay - University of Otago
Akos Heinemann - Medical University of Graz
Deron Herr - San Diego State University
Morley Hollenberg - University of Calgary
Nicholas Holliday - University of Nottingham
Mastgugu Horiuchi - Ehime University
Daniel Hoyer - University of Melbourne
László Hunyady - Semmelweis University
Ahsan Husain - Emory University
Adriaan Ijzerman - Leiden University
Tadashi Inagami - Vanderbilt University
Kenneth Jacobson - National Institutes of Health [Bethesda, MD, USA]
Robert Jensen - National Institutes of Health [Bethesda, MD, USA]
Ralf Jockers - Inserm
Deepa Jonnalagadda - Discovery Institute
Sadashiva Karnik - Lerner Research Institute [Cleveland, OH, USA]
Klemens Kaupmann - Novartis Foundation
Jacqueline Kemp - Cleveland Clinic Lerner College of Medicine
Charles Kennedy - University of Strathclyde
Yasuyuki Kihara - Discovery Institute
Takio Kitazawa - Rakuno Gakuen University
Pawel Kozielewicz - Karolinska Institutet
Hans‐jürgen Kreienkamp - Universität Hamburg
Jyrki Kukkonen - University of Helsinki
Tobias Langenhan - Leipzig University
Dan Larhammar - Uppsala University
Katie Leach - Monash University
Davide Lecca - University of Milan
John Lee - University of Queensland
Susan Leeman - Boston University
Jérôme Leprince - Université de Rouen Normandie
Xaria Li - University of Queensland
Stephen Lolait - University of Bristol
Amelie Lupp - Friedrich Schiller University Jena
Robyn Macrae - University of Cambridge
Janet Maguire - University of Cambridge
Davide Malfacini - University of Padua
Jean Mazella - Centre de Gestion Scientifique
Craig Mcardle - University of Bristol
Shlomo Melmed - Cedars-Sinai Medical Center
Martin Michel - Johannes Gutenberg University Mainz
Laurence Miller - Mayo Foundation
Vincenzo Mitolo - University of Bari Aldo Moro
Bernard Mouillac - Université de Montpellier, Institut de Génomique Fonctionnelle - IGF
Christa Müller - University of Bonn
Philip Murphy - Hill College
Jean‐Louis Nahon - Centre National de la Recherche Scientifique
Tony Ngo - Discovery Institute
Xavier Norel - Inserm
Duuamene Nyimanu - University of Cambridge
Anne‐marie O’carroll - University of Bristol
Stefan Offermanns - Max Planck Institute for Heart and Lung Research
Maria Antonietta Panaro - University of Bari Aldo Moro
Marc Parmentier - Université Libre de Bruxelles
Roger Pertwee - University of Aberdeen
Jean‐philippe Pin - Université de Montpellier, Institut de Génomique Fonctionnelle - IGF
Eric Prossnitz - University of New Mexico
Mark Quinn - Montana State University
Rithwik Ramachandran - University of Calgary
Manisha Ray - Discovery Institute
Rainer Reinscheid - Friedrich Schiller University Jena
Philippe Rondard - Université de Montpellier, Institut de Génomique Fonctionnelle - IGF
G. Enrico Rovati - University of Milan
Chiara Ruzza - University of Ferrara
Gareth Sanger - Queen Mary University of London
Torsten Schöneberg - Leipzig University
Gunnar Schulte - Karolinska Institutet
Stefan Schulz - Friedrich Schiller University Jena
Deborah Segaloff - University of Iowa
Charles Serhan - Harvard University Press
Khuraijam Dhanachandra Singh - Cleveland Clinic Lerner College of Medicine
Craig Smith - Deakin University
Leigh Stoddart - University of Nottingham
Yukihiko Sugimoto - Kumamoto University
Roger Summers - Monash University
Valerie Tan - University of California, San Diego
David Thal - Monash University
Walter Thomas - University of Queensland
Pieter Timmermans - Kosan Biosciences
Kalyan Tirupula - Cleveland Clinic Lerner College of Medicine
Lawrence Toll - Florida Atlantic University
Giovanni Tulipano - University of Brescia
Hamiyet Unal - Cleveland Clinic
Thomas Unger - Maastricht University
Celine Valant - Monash University
Patrick Vanderheyden - Université Libre de Bruxelles
David Vaudry - Université de Rouen Normandie
Hubert Vaudry - Université de Rouen Normandie
Jean‐pierre Vilardaga - Florida International University
Christopher Walker - University of Auckland
Ji Ming Wang - National Institutes of Health [Bethesda, MD, USA]
Donald Ward - University of Manchester
Hans‐jürgen Wester - Technical University of Munich
Gary Willars - University of Leicester
Tom Lloyd Williams - University of Cambridge
Trent Woodruff - University of Queensland
Chengcan Yao - University of Edinburgh
Richard Ye - Chinese University of Hong Kong, Shenzhen
Publication Details: British Journal of Pharmacology, Vol.180(S2), pp.S23-S144
Identifiers: 9933861009311
Academic Unit: Institut de Génomique Fonctionnelle - IGF
Language: English
Resource Type: Journal article
Local Fields: hal-04858591