Targeting multiplicity: the key factor for anti-cancer nanoparticles.

M. Gary-Bobo; O. Vaillant; M. Maynadier; I. Basile; A. Gallud; K. El Cheikh; E. Bouffard; A. Morere; X. Rébillard; P. Puche; P. Nirdé; M. Garcia

doi:10.2174/0929867311320150002

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Targeting multiplicity: the key factor for anti-cancer nanoparticles.

Journal article

Peer reviewed

Targeting multiplicity: the key factor for anti-cancer nanoparticles.

M. Gary-Bobo, O. Vaillant, M. Maynadier, I. Basile, A. Gallud, K. El Cheikh, E. Bouffard, A. Morere, X. Rébillard, P. Puche, …

Current Medicinal Chemistry, Vol.20(15), pp.1946-1955

2013

DOI: https://doi.org/10.2174/0929867311320150002

PMID: 23409718

Abstract

non-invasive therapy

Cancer

multiple targeting

nanoparticles

In this mini-review, we focus on different strategies to bring nanotools specifically to cancer cells. We discuss about a better targeting of tumor, combining the characteristics of tumor environment, the increase in nanoparticles life time, the biomarkers overexpressed on cancer cells and different physical methods for non invasive therapies. Here we detail the necessity of a synergy between passive and active targeting for an actual specificity of cancer cells.

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Title: Targeting multiplicity: the key factor for anti-cancer nanoparticles.
Creators - without role: M. Gary-Bobo - Université de Montpellier, Institut des Biomolécules Max Mousseron - IBMM
O. Vaillant - Université de Montpellier, Institut des Biomolécules Max Mousseron - IBMM
M. Maynadier - Université de Montpellier, Institut des Biomolécules Max Mousseron - IBMM
I. Basile - Université de Montpellier, Institut des Biomolécules Max Mousseron - IBMM
A. Gallud - Université de Montpellier, Institut des Biomolécules Max Mousseron - IBMM
K. El Cheikh - Université de Montpellier, Institut des Biomolécules Max Mousseron - IBMM
E. Bouffard - Université de Montpellier, Institut des Biomolécules Max Mousseron - IBMM
A. Morere - Université de Montpellier, Institut des Biomolécules Max Mousseron - IBMM
X. Rébillard - Université de Montpellier, Institut des Biomolécules Max Mousseron - IBMM
P. Puche - Université de Montpellier, Institut des Biomolécules Max Mousseron - IBMM
P. Nirdé - Université de Montpellier, Institut des Biomolécules Max Mousseron - IBMM
M. Garcia - Université de Montpellier, Institut des Biomolécules Max Mousseron - IBMM
Publication Details: Current Medicinal Chemistry, Vol.20(15), pp.1946-1955
Identifiers: 9942083709311
Academic Unit: Institut des Biomolécules Max Mousseron - IBMM
Language: English
Resource Type: Journal article
Local Fields: hal-00841552