Targeting epigenetics to speed up repair

Eric Soler; Frank Grosveld

doi:10.1016/j.stem.2014.04.018

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Targeting epigenetics to speed up repair

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Targeting epigenetics to speed up repair

Eric Soler et Frank Grosveld

Cell stem cell, Vol.14(5), pp.553-554

01/05/2014

DOI: https://doi.org/10.1016/j.stem.2014.04.018

PMID: 24792110

Résumé

Basic Helix-Loop-Helix Transcription Factors - metabolism

Endothelial Progenitor Cells - drug effects

Endothelial Progenitor Cells - metabolism

Humans

Hydroxamic Acids - pharmacology

Proto-Oncogene Proteins - metabolism

T-Cell Acute Lymphocytic Leukemia Protein 1

In this issue of Cell Stem Cell, Palii et al. reveal that TAL1 is a master regulator of adhesion and migration networks in human endothelial progenitors and that ex vivo treatment with the histone deacetylase inhibitor TSA enables their faster vascularization after ischemic injury.

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Détails

Titre: Targeting epigenetics to speed up repair
Créateurs - sans rôle: Eric Soler - Inserm
Frank Grosveld - Department of Cell Biology, Erasmus Medical Center, Rotterdam, The Netherlands. Electronic address: f.grosveld@erasmusmc.nl
Détails de publication: Cell stem cell, Vol.14(5), pp.553-554
Identifiants: 99139664209311
Unité académique: Institut de Génétique Moléculaire de Montpellier - IGMM
Langue: English
Type de ressource: Journal article