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Synthesis of New Ethyl 3-Amino-4-arylfuran-2-carboxylates
Article de revue   Avec comité de lecture

Synthesis of New Ethyl 3-Amino-4-arylfuran-2-carboxylates

Vincent Lisowski, Duc Nghia Vu, Xiao Feng et Sylvain Rault
Synthesis (Stuttgart), Vol.2002(6), pp.753-756
2002

Résumé

paper
ABSTRACT An efficient method for the preparation of new ethyl 3-amino-4-arylfuran-2-carboxylates is described. The synthesis proceeds via the corresponding hydroxyacrylonitrile sodium salt and an intermediate malonate vinyl ether. The last step of ring closure afforded the ethyl 3-amino-4-arylfuran-2-carboxylates in 15% to 40% yields.

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