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Synthesis of 4,5-dihydropyrazolyl-2H-indenediones by aldol condensation of ninhydrin with 1H-pyrazol-5-ol
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Synthesis of 4,5-dihydropyrazolyl-2H-indenediones by aldol condensation of ninhydrin with 1H-pyrazol-5-ol

Ebrahim Soleimani, Mina Hariri, Arman Rostamzadeh et Somayeh Ghorbani
Journal of chemical research, Vol.40(11), pp.664-666
01/11/2016

Résumé

Chemistry Chemistry, Multidisciplinary Physical Sciences Science & Technology
A simple and efficient procedure for the synthesis of 2-hydroxy-2-(5-hydroxy-1H-pyrazol-4-yl)-2H-indene-1,3-dione derivatives, proceeding via aldol condensation between ninhydrin and various 3-alkyl-1H-pyrazol-5-ols is described. The syntheses were carried out in ethanol at room temperature and proceeded with short reaction times to give the products with high yields.

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