Syntheses of (S,S)-reboxetine via a catalytic stereospecific rearrangement of beta-amino alcohols

Thomas-Xavier Métro; Domingo Gomez Pardo; Janine Cossy

doi:10.1021/jo701554h

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Syntheses of (S,S)-reboxetine via a catalytic stereospecific rearrangement of beta-amino alcohols

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Syntheses of (S,S)-reboxetine via a catalytic stereospecific rearrangement of beta-amino alcohols

Thomas-Xavier Métro, Domingo Gomez Pardo et Janine Cossy

Journal of organic chemistry, Vol.73(2), pp.707-710

18/01/2008

DOI: https://doi.org/10.1021/jo701554h

PMID: 18092801

Résumé

Amino Alcohols - chemistry

Catalysis

Molecular Conformation

Morpholines - chemical synthesis

Morpholines - chemistry

Stereoisomerism

The formal total synthesis of (S,S)-reboxetine has been realized by two different approaches using a stereospecific rearrangement of beta-amino alcohols catalyzed by (CF3CO)2O.

Indicateurs

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Détails

Titre: Syntheses of (S,S)-reboxetine via a catalytic stereospecific rearrangement of beta-amino alcohols
Créateurs - sans rôle: Thomas-Xavier Métro - Laboratoire de Chimie Organique
Domingo Gomez Pardo
Janine Cossy
Détails de publication: Journal of organic chemistry, Vol.73(2), pp.707-710
Identifiants: 99138952009311
Unité académique: Institut Charles Gerhardt Montpellier - ICGM
Langue: English
Type de ressource: Journal article