Structure of Chimpanzee Gut Microbiomes across Tropical Africa

Clifton P. Bueno de Mesquita; Lauren M. Nichols; Matthew J. Gebert; Caihong Vanderburgh; Gaëlle Bocksberger; Jack D. Lester; Ammie K. Kalan; Paula Dieguez; Maureen S. McCarthy; Anthony Agbor; Paula Álvarez Varona; Ayuk Emmanuel Ayimisin; Mattia Bessone; Rebecca Chancellor; Heather Cohen; Charlotte Coupland; Tobias Deschner; Villard Ebot Egbe; Annemarie Goedmakers; Anne-Céline Granjon; Cyril C. Grueter; Josephine Head; R. Adriana Hernandez-Aguilar; Kathryn J. Jeffery; Sorrel Jones; Parag Kadam; Michael Kaiser; Juan Lapuente; Bradley Larson; Sergio Marrocoli; David Morgan; Badru Mugerwa; Felix Mulindahabi; Emily Neil; Protais Niyigaba; Liliana Pacheco; Alex K. Piel; Martha M. Robbins; Aaron Rundus; Crickette M. Sanz; Lilah Sciaky; Douglas Sheil; Volker Sommer; Fiona A. Stewart; Els Ton; Joost van Schijndel; Virginie Vergnes; Erin G. Wessling; Roman M. Wittig; Yisa Ginath Yuh; Kyle Yurkiw; Klaus Zuberbühler; Jan F. Gogarten; Anna Heintz-Buschart; Alexandra N. Muellner-Riehl; Christophe Boesch; Hjalmar S. Kühl; Noah Fierer; Mimi Arandjelovic; Robert R. Dunn

doi:10.1128/mSystems.01269-20

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Structure of Chimpanzee Gut Microbiomes across Tropical Africa

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Structure of Chimpanzee Gut Microbiomes across Tropical Africa

Clifton P. Bueno de Mesquita, Lauren M. Nichols, Matthew J. Gebert, Caihong Vanderburgh, Gaëlle Bocksberger, Jack D. Lester, Ammie K. Kalan, Paula Dieguez, Maureen S. McCarthy, Anthony Agbor, …

mSystems, Vol.6(3), p.e0126920

29/06/2021

DOI: https://doi.org/10.1128/mSystems.01269-20

PMID: 34156289

Résumé

Gut microbial communities are drivers of primate physiology and health, but the factors that influence the gut microbiome in wild primate populations remain largely undetermined. We report data from a continent-wide survey of wild chimpanzee gut microbiota and highlight the effects of genetics, vegetation, and potentially even tool use at different spatial scales on the chimpanzee gut microbiome, including bacteria, archaea, and eukaryotic parasites. Understanding variation in host-associated microbial communities is important given the relevance of microbiomes to host physiology and health. Using 560 fecal samples collected from wild chimpanzees ( Pan troglodytes ) across their range, we assessed how geography, genetics, climate, vegetation, and diet relate to gut microbial community structure (prokaryotes, eukaryotic parasites) at multiple spatial scales. We observed a high degree of regional specificity in the microbiome composition, which was associated with host genetics, available plant foods, and potentially with cultural differences in tool use, which affect diet. Genetic differences drove community composition at large scales, while vegetation and potentially tool use drove within-region differences, likely due to their influence on diet. Unlike industrialized human populations in the United States, where regional differences in the gut microbiome are undetectable, chimpanzee gut microbiomes are far more variable across space, suggesting that technological developments have decoupled humans from their local environments, obscuring regional differences that could have been important during human evolution. IMPORTANCE Gut microbial communities are drivers of primate physiology and health, but the factors that influence the gut microbiome in wild primate populations remain largely undetermined. We report data from a continent-wide survey of wild chimpanzee gut microbiota and highlight the effects of genetics, vegetation, and potentially even tool use at different spatial scales on the chimpanzee gut microbiome, including bacteria, archaea, and eukaryotic parasites. Microbial community dissimilarity was strongly correlated with chimpanzee population genetic dissimilarity, and vegetation composition and consumption of algae, honey, nuts, and termites were potentially associated with additional divergence in microbial communities between sampling sites. Our results suggest that host genetics, geography, and climate play a far stronger role in structuring the gut microbiome in chimpanzees than in humans.

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Titre: Structure of Chimpanzee Gut Microbiomes across Tropical Africa
Créateurs - sans rôle: Clifton P. Bueno de Mesquita - Department of Ecology and Evolutionary Biology, University of Colorado, Boulder, Colorado, USA, Cooperative Institute for Research in Environmental Sciences, University of Colorado, Boulder, Colorado, USA
Lauren M. Nichols - Department of Applied Ecology, North Carolina State University, Raleigh, North Carolina, USA
Matthew J. Gebert - Department of Ecology and Evolutionary Biology, University of Colorado, Boulder, Colorado, USA, Cooperative Institute for Research in Environmental Sciences, University of Colorado, Boulder, Colorado, USA
Caihong Vanderburgh - Department of Ecology and Evolutionary Biology, University of Colorado, Boulder, Colorado, USA, Cooperative Institute for Research in Environmental Sciences, University of Colorado, Boulder, Colorado, USA
Gaëlle Bocksberger - Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany
Jack D. Lester - Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany
Ammie K. Kalan - Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany
Paula Dieguez - Max Planck Institute for Evolutionary Anthropology
Maureen S. McCarthy - Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany
Anthony Agbor - Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany
Paula Álvarez Varona - Jane Goodall Institute Spain and Sénégal, Dindefelo Biological Station, Dindefelo, Kedougou, Sénégal
Ayuk Emmanuel Ayimisin - Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany
Mattia Bessone - Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany, School of Biological & Environmental Sciences, Liverpool John Moores University, Liverpool, United Kingdom
Rebecca Chancellor - Department of Psychology, West Chester University, West Chester, Pennsylvania, USA, Department of Anthropology & Sociology, West Chester University, West Chester, Pennsylvania, USA
Heather Cohen - Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany
Charlotte Coupland - Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany
Tobias Deschner - Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany
Villard Ebot Egbe - Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany
Annemarie Goedmakers - Chimbo Foundation, Oudemirdum, The Netherlands
Anne-Céline Granjon - Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany
Cyril C. Grueter - School of Human Sciences, University of Western Australia, Perth, Australia, School of Biological Sciences, University of Western Australia, Perth, Australia, International Centre of Biodiversity and Primate Conservation, Dali University, Dali, Yunnan, China
Josephine Head - Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany
R. Adriana Hernandez-Aguilar - Jane Goodall Institute Spain and Sénégal, Dindefelo Biological Station, Dindefelo, Kedougou, Sénégal, Department of Social Psychology and Quantitative Psychology, Faculty of Psychology, University of Barcelona, Barcelona, Spain
Kathryn J. Jeffery - School of Natural Sciences, University of Stirling, Stirling, United Kingdom
Sorrel Jones - Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany, Royal Society for the Protection of Birds, Cambridge, United Kingdom
Parag Kadam - Greater Mahale Ecosystem Research and Conservation Project, Tanzania
Michael Kaiser - Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany
Juan Lapuente - Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany, Comoé Chimpanzee Conservation Project, Kakpin, Comoé National Park, Ivory Coast
Bradley Larson - Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany
Sergio Marrocoli - Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany
David Morgan - Lester E. Fisher Center for the Study and Conservation of Apes, Lincoln Park Zoo, Chicago, Illinois, USA
Badru Mugerwa - Leibniz Institute for Zoo and Wildlife Research, Berlin, Germany, Institute of Tropical Forest Conservation (ITFC), Mbarara University of Science and Technology (MUST), Kabale, Uganda
Felix Mulindahabi - Wildlife Conservation Society, Bronx, New York, USA
Emily Neil - Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany
Protais Niyigaba - Wildlife Conservation Society, Bronx, New York, USA
Liliana Pacheco - Projet GALF-Guinée, Wara Conservation Project, Guinea
Alex K. Piel - Greater Mahale Ecosystem Research and Conservation Project, Tanzania, Department of Anthropology, University College London, London, United Kingdom
Martha M. Robbins - Max Planck Institute for Evolutionary Anthropology
Aaron Rundus - Department of Psychology, West Chester University, West Chester, Pennsylvania, USA
Crickette M. Sanz - Wildlife Conservation Society, Bronx, New York, USA, Department of Anthropology, Washington University in Saint Louis, St. Louis, Missouri, USA
Lilah Sciaky - Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany
Douglas Sheil - Wageningen University & Research
Volker Sommer - Department of Anthropology, University College London, London, United Kingdom, Gashaka Primate Project, Serti, Nigeria
Fiona A. Stewart - School of Biological & Environmental Sciences, Liverpool John Moores University, Liverpool, United Kingdom, Greater Mahale Ecosystem Research and Conservation Project, Tanzania, Department of Anthropology, University College London, London, United Kingdom
Els Ton - Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany, Chimbo Foundation, Oudemirdum, The Netherlands
Joost van Schijndel - Max Planck Institute for Evolutionary Anthropology
Virginie Vergnes - Wild Chimpanzee Foundation
Erin G. Wessling - Department of Human Evolutionary Biology, Harvard University, Cambridge, Massachusetts, USA
Roman M. Wittig - Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany, Taï Chimpanzee Project, CSRS, Abidjan, Ivory Coast
Yisa Ginath Yuh - Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany, Department of Geography, Planning and Environmental Studies, University of Concordia, Montréal, Quebec, Canada
Kyle Yurkiw - Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany
Klaus Zuberbühler - Institut de Biologie, Université de Neuchâtel, Neuchâtel, Switzerland, School of Psychology and Neuroscience, University of St. Andrews, St. Andrews, United Kingdom
Jan F. Gogarten - Epidemiology of Highly Pathogenic Microorganisms, Robert Koch Institute, Berlin, Germany, Viral Evolution Project Group, Robert Koch Institute, Berlin, Germany
Anna Heintz-Buschart - German Centre for Integrative Biodiversity Research (iDiv) Halle-Jena-Leipzig, Leipzig, Germany, Department of Soil Ecology, Helmholtz Centre for Environmental Research GmbH - UFZ, Halle, Germany
Alexandra N. Muellner-Riehl - Leipzig University
Christophe Boesch - Max Planck Institute for Evolutionary Anthropology
Hjalmar S. Kühl - Max Planck Institute for Evolutionary Anthropology
Noah Fierer - Department of Ecology and Evolutionary Biology, University of Colorado, Boulder, Colorado, USA, Cooperative Institute for Research in Environmental Sciences, University of Colorado, Boulder, Colorado, USA
Mimi Arandjelovic - Max Planck Institute for Evolutionary Anthropology
Robert R. Dunn - North Carolina State University
Détails de publication: mSystems, Vol.6(3), p.e0126920
Identifiants: 99149227109311
Unité académique: BotAnique et Modélisation de l'Architecture des Plantes et des végétations - AMAP
Langue: English
Type de ressource: Journal article