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Stricturing Crohn's disease-like colitis in a patient treated with belatacept
Journal article   Open access   Peer reviewed

Stricturing Crohn's disease-like colitis in a patient treated with belatacept

Anne Bozon, Guillaume Jeantet, Benjamin Rivière, Natalie Funakoshi, Gaspard Dufour, Roman Combes, Jean-Christophe Valats, Sylvie Delmas, Jean Emmanuel Serre, Michael Bismuth, …
World Journal of Gastroenterology, Vol.23(48), pp.8660--8665
2017
PMCID: PMC5752725
PMID: 29358873

Abstract

Crohn's disease Colitis Belatacept Inflammatory bowel disease HHV-6
Cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) modifying agents have been involved in the development of intestinal inflammation, especially therapeutic monoclonal antibodies directed against CTLA-4. Here we report the appearance of a severe stricturing Crohn's disease-like colitis in a patient with a kidney allograft who was treated with belatacept, a recombinant CTLA-4-Ig fusion protein.
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