Sphincter-saving surgery after neoadjuvant therapy for ultra-low rectal cancer where abdominoperineal resection was indicated: 10-year results of the GRECCAR 1 trial

P. Rouanet; M. Rivoire; S. Gourgou; B. Lelong; E. Rullier; M. Jafari; L. Mineur; M. Pocard; J. L. Faucheron; F. Dravet; D. Pezet; J. M. Fabre; L. Bresler; J. Balosso; C. Lemanski

doi:10.1093/bjs/znaa010

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Sphincter-saving surgery after neoadjuvant therapy for ultra-low rectal cancer where abdominoperineal resection was indicated: 10-year results of the GRECCAR 1 trial

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Sphincter-saving surgery after neoadjuvant therapy for ultra-low rectal cancer where abdominoperineal resection was indicated: 10-year results of the GRECCAR 1 trial

P. Rouanet, M. Rivoire, S. Gourgou, B. Lelong, E. Rullier, M. Jafari, L. Mineur, M. Pocard, J. L. Faucheron, F. Dravet, …

British journal of surgery, Vol.108(1), pp.10-13

27/01/2021

DOI: https://doi.org/10.1093/bjs/znaa010

Résumé

Life Sciences & Biomedicine

Science & Technology

Surgery

This phase III trial included patients with ultra-low rectal adenocarcinoma that initially required abdominoperineal resection. The surgical decision was based on clinical tumour status after preoperative treatment. The overall sphincter-saving resection rate was 85 per cent, with 72 per cent rate of intersphincteric resection. Long-term results showed that changing the initial abdominoperineal resection indication into a sphincter-saving resection according to tumoral response is oncologically safe. Saving the sphincter

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Titre: Sphincter-saving surgery after neoadjuvant therapy for ultra-low rectal cancer where abdominoperineal resection was indicated: 10-year results of the GRECCAR 1 trial
Créateurs - sans rôle: P. Rouanet - Inst Reg Canc Montpellier Val Aurelle, Dept Surg Oncol, Montpellier, France
M. Rivoire - Ctr Leon Berard, Dept Surg Oncol, Lyon, France
S. Gourgou - Montpellier Canc Inst, Biometr Unit, Montpellier, France
B. Lelong - Inst Paoli Calmettes, Dept Surg Oncol, Marseille, France
E. Rullier - Ctr Hosp Univ Bordeaux, Colorectal Dept, Bordeaux, France
M. Jafari - Ctr Oscar Lambret, Dept Surg Oncol, Lille, France
L. Mineur - Inst St Catherine, Dept Radiat Oncol, Avignon, France
M. Pocard - Hop Lariboisiere, Assistance Publ Hop Paris, Gustave Roussy, Dept Surg Oncol, Paris, France
J. L. Faucheron - Ctr Hosp Univ Grenoble, Colorectal Dept, Grenoble, France
F. Dravet - Ctr Rene Gauducheau, Dept Surg Oncol, Nantes, France
D. Pezet - Ctr Hosp Univ Clermont Ferrand, Colorectal Dept, Clermont Ferrand, France
J. M. Fabre - Ctr Hosp Univ Montpellier, Colorectal Dept, Montpellier, France
L. Bresler - Ctr Hosp Univ Nancy, Colorectal Dept, Nancy, France
J. Balosso - Ctr Hosp Univ Grenoble, Dept Radiotherapy, Grenoble, France
C. Lemanski - Inst Reg Canc Montpellier Val Aurelle, Dept Radiotherapy, Montpellier, France
Détails de publication: British journal of surgery, Vol.108(1), pp.10-13
Éditeur: Oxford Univ Press
Nombre de pages: 4
Identifiants: 99148933409311
Unité académique: Recherche hors université
Langue: English
Type de ressource: Journal article