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Simultaneous control of flotation and release kinetics from clay-containing pellets designed for oral delivery of some trace elements.R. Odilon Kikouama, P. Legrand, N. Yagoubi, L. Baldé, G. Ponchel
Journal article   Peer reviewed

Simultaneous control of flotation and release kinetics from clay-containing pellets designed for oral delivery of some trace elements.R. Odilon Kikouama, P. Legrand, N. Yagoubi, L. Baldé, G. Ponchel

Odilon Kikouama, Philippe Legrand, Najet Yagoubi, Lamine Baldé and Gilles Ponchel
Journal of Drug Delivery Science and Technology, Vol.18(2), pp.128-135
01/03/2008
DOI: https://doi.org/10.1016/S1773-2247(08)50020-7

Abstract

Controlled release Controlled release. Floating pellets Coating Extrusion-spheronization Clay powder formulation Trace elements
A gastroretentive floating dosage form, composed of a multiple-unit pellet system containing significant amounts of a clay powder used as a source of trace elements including iron and zinc has been developed, with its formulation based on the use of conventional polymeric and mineral excipients
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