Severe chronic allergic (and related) diseases: a uniform approach--a MeDALL--GA2LEN--ARIA position paper.

Jean Bousquet; Josep M. Anto; Pascal Demoly; Holger J. Schünemann; Alkis Togias; Mübeccel Akdis; Charles Auffray; Claus Bachert; Thomas Bieber; Philippe J. Bousquet; Kai-Håkon Carlsen; Thomas B. Casale; Alavaro A. Cruz; Thomas Keil; Karin C. Lodrup Carlsen; Marcus Maurer; K. Ohta; N. G. Papadopoulos; M. Roman Rodriguez; B. Samolinski; I. Agache; A. Andrianarisoa; Isabella Annesi-Maesano; F. Ballester; C. E. Baena-Cagnani; X. Basagaña; E. D. Bateman; E. H. Bel; A. Bedbrook; B. Beghé; M. Beji; Ali Ben Kheder; M. Benet; Kazi Saifuddin Bennoor; K. C. Bergmann; Fouad Berrissoul; Carsten Bindslev Jensen; Eugene R. Bleecker; S. Bonini; A. L. Boner; L. P. Boulet; Christopher E. Brightling; Jan L. Brozek; Andrew Bush; W. W. Busse; Paulo Augusto Moreira Camargos; Giorgio Walter Canonica; Warner Carr; Alfredo Cesario; Y. Z. Chen; A. M. Chiriac; David J. Costa; Latonia Cox; Adnan Custovic; Ronald Dahl; Ulf Darsow; Toufik Didi; Habib Douagui; Ruta Dubakiene; Abdellah El-Meziane; Joao A. Fonseca; W. J. Fokkens; E. Fthenou; Amiran Gamkrelidze; J. Garcia-Aymerich; Roy Gerth van Wijk; E. Gimeno-Santos; Stefano Guerra; Tari Haahtela; H. Haddad; Peter W. Hellings; B. Hellquist-Dahl; C. Hohmann; Peter Howarth; J. O. Hourihane; Marc Humbert; Bénédicte Jacquemin; Jocelyne Just; Omer Kalayci; Michael A. Kaliner; Francine Kauffmann; Marjan Kerkhof; G. Khayat; Bernard Koffi N'Goran; M. Kogevinas; Gerard H. Koppelman; Marek L. Kowalski; Inger Kull; Piotr Kuna; Désirée Larenas; I. Lavi; Lan Thi Tuyet Le; Phil Lieberman; Brian J. Lipworth; Bassam H. Mahboub; M. J. Makela; Francis Martin; Fernando D. Martinez; Gailen D. Marshall; A. Mazon; Erik Melen; Eli O. Meltzer; F. Mihaltan; Yousser Mohammad; Azzeddine Mohammadi; Isabelle Momas; Mario Morais-Almeida; Joaquim Mullol; Antonella Muraro; Robert Naclerio; Salim Nafti; Leyla Namazova-Baranova; Martijn C. Nawijn; Tshipukane Dieudonné Nyembue; Sam Oddie; Robyn E. O'Hehir; Yoshitaka Okamoto; M. P. Orru; Cevdet Ozdemir; G. S. Ouedraogo; Susanna Palkonen; Petr Panzner; G. Passalacqua; Ruby Pawankar; Bernard Pigearias; Isabelle Pin; M. Pinart; Christophe Pison; Ted A. Popov; Daniela Porta; Dirkje S. Postma; David Price; Klaus F. Rabe; Julia Ratomaharo; S. Reitamo; Djamel Rezagui; Johannes Ring; R. Roberts; Joseph Roca; B. Rogala; Antonino Romano; José Rosado-Pinto; Dermot Ryan; Mario Sanchez-Borges; Glenis K. Scadding; Aziz Sheikh; Frances Estelle Reed Simons; Valérie Siroux; Peter D. Schmid-Grendelmeier; H. A. Smit; Talant M. Sooronbaev; Renato Tetelbom Stein; P. J. Sterk; J. Sunyer; Ingrid Terreehorst; Elina Toskala; Yves Tremblay; Rudolf Valenta; Dominique Valeyre; Olivier Vandenplas; Chris van Weel; M. Vassilaki; R. Varraso; Giovanni Viegi; de Yun Wang; Magnus Wickman; Dennis Williams; Stefan Wöhrl; J. Wright; Arzu Yorgancioglu; Osman M. Yusuf; H. J. Zar; M. E. Zernotti; Mihaela Zidarn; N. Zhong; Torsten Zuberbier

doi:10.1159/000332924

Back

Severe chronic allergic (and related) diseases: a uniform approach--a MeDALL--GA2LEN--ARIA position paper.

Journal article

Open access

Peer reviewed

Severe chronic allergic (and related) diseases: a uniform approach--a MeDALL--GA2LEN--ARIA position paper.

Jean Bousquet, Josep M. Anto, Pascal Demoly, Holger J. Schünemann, Alkis Togias, Mübeccel Akdis, Charles Auffray, Claus Bachert, Thomas Bieber, Philippe J. Bousquet, …

International Archives of Allergy and Immunology, Vol.158(3), pp.216-31

2012

DOI: https://doi.org/10.1159/000332924

PMID: 22382913

Abstract

IgE

allergy

severity

control

risk

asthma

rhinitis

rhinosinusitis

urticaria

atopic dermatitis

Chronic Disease

Urticaria

Asthma

Comorbidity

Dermatitis, Atopic

Humans

Hypersensitivity

Practice Guidelines as Topic

Rhinitis

Severity of Illness Index

Sinusitis

Concepts of disease severity, activity, control and responsiveness to treatment are linked but different. Severity refers to the loss of function of the organs induced by the disease process or to the occurrence of severe acute exacerbations. Severity may vary over time and needs regular follow-up. Control is the degree to which therapy goals are currently met. These concepts have evolved over time for asthma in guidelines, task forces or consensus meetings. The aim of this paper is to generalize the approach of the uniform definition of severe asthma presented to WHO for chronic allergic and associated diseases (rhinitis, chronic rhinosinusitis, chronic urticaria and atopic dermatitis) in order to have a uniform definition of severity, control and risk, usable in most situations. It is based on the appropriate diagnosis, availability and accessibility of treatments, treatment responsiveness and associated factors such as comorbidities and risk factors. This uniform definition will allow a better definition of the phenotypes of severe allergic (and related) diseases for clinical practice, research (including epidemiology), public health purposes, education and the discovery of novel therapies.

Files and links (1)

url

Find in HALView

Metrics

1 Record Views

See more details

Details

Title: Severe chronic allergic (and related) diseases: a uniform approach--a MeDALL--GA2LEN--ARIA position paper.
Creators - without role: Jean Bousquet - Hôpital Arnaud de Villeneuve
Josep M. Anto - Center for Research in Environmental Epidemiology
Pascal Demoly - WHO Collaborating Center for Asthma and Rhinitis
Holger J. Schünemann - McMaster University
Alkis Togias - National Institutes of Health
Mübeccel Akdis - University of Zurich
Charles Auffray - Centre de Gestion Scientifique
Claus Bachert - Ghent University Hospital
Thomas Bieber - University of Bonn
Philippe J. Bousquet - Hôpital Arnaud de Villeneuve
Kai-Håkon Carlsen - Department of Paediatrics
Thomas B. Casale - Creighton University
Alavaro A. Cruz - ProAR - FMB
Thomas Keil - Charité - Universitätsmedizin Berlin
Karin C. Lodrup Carlsen - Department of Paediatrics
Marcus Maurer - Charité - Universitätsmedizin Berlin
K. Ohta - Teikyo University Hospital
N. G. Papadopoulos - National and Kapodistrian University of Athens
M. Roman Rodriguez - Son Pisa Primary Care Centre
B. Samolinski - Medical University of Warsaw
I. Agache - Department of Allergy and Clinical Immunology
A. Andrianarisoa - Public Hospital Medical Service
Isabella Annesi-Maesano - Epidémiologie des maladies infectieuses et modélisation
F. Ballester - Universitat de València
C. E. Baena-Cagnani - Charité - Universitätsmedizin Berlin
X. Basagaña - Municipal Institute for Medical Research
E. D. Bateman - University of Cape Town
E. H. Bel - University of Amsterdam
A. Bedbrook - WHO Collaborating Center for Asthma and Rhinitis
B. Beghé - University of Southampton
M. Beji - Tunis El Manar University
Ali Ben Kheder - Tunis El Manar University
M. Benet - Municipal Institute for Medical Research
Kazi Saifuddin Bennoor - National Asthma Centre
K. C. Bergmann - Charité - Universitätsmedizin Berlin
Fouad Berrissoul - Pneumologie / Anesthésie - réanimation / Oxygénothérapie
Carsten Bindslev Jensen - Department of Dermatology and Allergy Center
Eugene R. Bleecker - Wake Forest University
S. Bonini - Institute of Neurobiology and Molecular Medicine
A. L. Boner - University of Verona
L. P. Boulet - Université Laval
Christopher E. Brightling - University of Leicester
Jan L. Brozek - McMaster University
Andrew Bush - Imperial College London
W. W. Busse - University of Wisconsin–Madison
Paulo Augusto Moreira Camargos - Universidade Federal de Minas Gerais
Giorgio Walter Canonica - University of Genoa
Warner Carr - Allergy & Asthma Associates
Alfredo Cesario - Università Cattolica del Sacro Cuore
Y. Z. Chen - National Cooperative Group of Pediatric Research on Asthma
A. M. Chiriac - Hôpital Arnaud de Villeneuve
David J. Costa - Université de Montpellier
Latonia Cox - Osteopathic College of Medicine
Adnan Custovic - University of Manchester
Ronald Dahl - Aarhus University
Ulf Darsow - Technical University of Munich
Toufik Didi - Service de pneumologie
Habib Douagui - Service de pneumo-allergologie
Ruta Dubakiene - Vilnius University
Abdellah El-Meziane - Société Marocaine des Maladies Respiratoires
Joao A. Fonseca - Universidade do Porto
W. J. Fokkens - University of Amsterdam
E. Fthenou - Crete University Press
Amiran Gamkrelidze - Health Care
J. Garcia-Aymerich - Center for Research in Environmental Epidemiology
Roy Gerth van Wijk - Section of Allergology
E. Gimeno-Santos - Municipal Institute for Medical Research
Stefano Guerra - University of Arizona
Tari Haahtela - Department of Dermatology
H. Haddad - Service de pneumologie
Peter W. Hellings - KU Leuven
B. Hellquist-Dahl - Aarhus University
C. Hohmann - Charité - Universitätsmedizin Berlin
Peter Howarth - University of Southampton
J. O. Hourihane - Paediatrics and Child Health
Marc Humbert - Université Paris-Saclay
Bénédicte Jacquemin - Centre de recherche en Epidémiologie et Santé des Populations
Jocelyne Just - Charmo University
Omer Kalayci - Pediatric Allergy and Asthma Unit
Michael A. Kaliner - Washington University in St. Louis
Francine Kauffmann - Centre de recherche en Epidémiologie et Santé des Populations
Marjan Kerkhof - University of Groningen
G. Khayat - Saint Joseph's University
Bernard Koffi N'Goran - Service des Maladies Respiratoires
M. Kogevinas - Municipal Institute for Medical Research
Gerard H. Koppelman - University of Groningen
Marek L. Kowalski - Department of Clinical Immunology and Allergy
Inger Kull - Karolinska Institutet
Piotr Kuna - Division of Internal Medicine, Asthma and Allergy
Désirée Larenas - Allergy Department
I. Lavi - Municipal Institute for Medical Research
Lan Thi Tuyet Le - Physiology Department
Phil Lieberman - University of Tennessee Health Science Center
Brian J. Lipworth - University of Dundee
Bassam H. Mahboub - University of Sharjah
M. J. Makela - Department of Dermatology
Francis Martin - Association Franco-Vietnamienne de Pneumologie
Fernando D. Martinez - University of Arizona
Gailen D. Marshall - University of Mississippi
A. Mazon - Universitat de València
Erik Melen - Karolinska Institutet
Eli O. Meltzer - University of California, San Diego
F. Mihaltan - Pneumology Department
Yousser Mohammad - Tishreen University
Azzeddine Mohammadi - Association Franco-Marocaine de Pathologie Thoracique
Isabelle Momas - Université Paris Cité
Mario Morais-Almeida - Immunoallergy Department
Joaquim Mullol - Universitat de Barcelona
Antonella Muraro - University of Padua
Robert Naclerio - University of Chicago
Salim Nafti - Clinique des maladies respiratoires
Leyla Namazova-Baranova - Russian Academy of Sciences
Martijn C. Nawijn - University of Groningen
Tshipukane Dieudonné Nyembue - ENT Department
Sam Oddie - Bradford Neonatology
Robyn E. O'Hehir - Department of Allergy, Immunology and Respiratory Medicine
Yoshitaka Okamoto - Chiba University
M. P. Orru - American Pharmacists Association
Cevdet Ozdemir - Marmara University
G. S. Ouedraogo - Pédiatrie
Susanna Palkonen - European Federation of Allergy
Petr Panzner - Charles University
G. Passalacqua - University of Genoa
Ruby Pawankar - Nippon Medical School
Bernard Pigearias - Laboratoire du Sommeil et de l'Effort
Isabelle Pin - Université Grenoble Alpes
M. Pinart - Municipal Institute for Medical Research
Christophe Pison - Université Grenoble Alpes
Ted A. Popov - Clinic of Allergy and Asthma
Daniela Porta - Department of Epidemiology
Dirkje S. Postma - University of Groningen
David Price - University of Aberdeen
Klaus F. Rabe - Leiden University
Julia Ratomaharo - Pneumalgia
S. Reitamo - Epidemiology and Biostatistics Division
Djamel Rezagui - Association Franco-Algérienne de Pneumologie
Johannes Ring - Technical University of Munich
R. Roberts - University of Wisconsin–Madison
Joseph Roca - Department of Pneumology
B. Rogala - University of Silesia in Katowice
Antonino Romano - Università Cattolica del Sacro Cuore
José Rosado-Pinto - Immunoallergy Department
Dermot Ryan - University of Aberdeen
Mario Sanchez-Borges - Department of Allergy and Clinical Immunology
Glenis K. Scadding - University College London
Aziz Sheikh - University of Edinburgh
Frances Estelle Reed Simons - University of Manitoba
Valérie Siroux - Inserm
Peter D. Schmid-Grendelmeier - University of Zurich
H. A. Smit - Utrecht University
Talant M. Sooronbaev - National Centre of Cardiology and Internal Medicine
Renato Tetelbom Stein - Pontifícia Universidade Católica do Rio Grande do Sul
P. J. Sterk - University of Amsterdam
J. Sunyer - Center for Research in Environmental Epidemiology
Ingrid Terreehorst - Amsterdam University of the Arts
Elina Toskala - Department of Otorhinolaryngology
Yves Tremblay - Université Laval
Rudolf Valenta - Medical University of Vienna
Dominique Valeyre - Université Paris Cité
Olivier Vandenplas - Department of Chest Medicine
Chris van Weel - Radboud University Nijmegen
M. Vassilaki - Crete University Press
R. Varraso - Centre de recherche en Epidémiologie et Santé des Populations
Giovanni Viegi - Epidemiology Unit
de Yun Wang - National University of Singapore
Magnus Wickman - Karolinska Institutet
Dennis Williams - GLP Analytical Facility
Stefan Wöhrl - Medical University of Vienna
J. Wright - Bradford Neonatology
Arzu Yorgancioglu - Department of Pulmonology
Osman M. Yusuf - Allergy and Asthma Clinics
H. J. Zar - University of Cape Town
M. E. Zernotti - Catholic University of America
Mihaela Zidarn - University of Ljubljana
N. Zhong - Guangzhou Medical University
Torsten Zuberbier - Charité - Universitätsmedizin Berlin
Publication Details: International Archives of Allergy and Immunology, Vol.158(3), pp.216-31
Identifiers: 9939589709311
Academic Unit: Institut Desbrest d Epidemiologie et de Sante Publique - IDESP
Language: English
Resource Type: Journal article
Local Fields: inserm-00788048