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Revisiting the cardiovascular risk of hydroxychloroquine in RA
Journal article   Open access

Revisiting the cardiovascular risk of hydroxychloroquine in RA

Yves-Marie Pers and Guillaume Padern
Nature Reviews Rheumatology, Vol.16(12), pp.671-672
12/2020
PMCID: PMC7525224
PMID: 32999492

Abstract

Anti-Bacterial Agents Anti-Infective Agents Hydroxychloroquine SARS-CoV-2 Safety Sulfasalazine Time Factors Antimalarials Arthritis, Rheumatoid Azithromycin COVID-19 Cardiovascular Diseases Drug Therapy, Combination Heart Disease Risk Factors Humans
Cardiac toxicity can be induced by hydroxychloroquine, especially when used in combination with azithromycin. Interest in hydroxychloroquine and azithromycin as potential therapies for COVID-19 has renewed concerns about the possible cardiovascular risk these drugs present to patients with rheumatoid arthritis.
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