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Rethinking the Microprocessor
Article de revue   Avec comité de lecture

Rethinking the Microprocessor

Hervé Seitz et Phillip D. Zamore
Cell, Vol.125(5), pp.827-829
02/06/2006
PMID: 16751089

Résumé

MicroRNAs (miRNAs) are tiny regulators of gene expression that are processed from longer primary transcripts. In this issue, Han et al. (2006) report some of the structural features of the primary transcript that ensure that the Drosha-DGCR8 enzyme complex liberates precisely the correct precursor sequence, enabling production of a fully functional miRNA.

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