Response to biologics along a gradient of T2 involvement in patients with severe asthma: a data-driven biomarker clustering approach

Eileen Wang; William Henley; Désirée Larenas-Linnemann; Lakmini Bulathsinhala; Trung Tran; Michael Wechsler; Shawn Aaron; Mona Al-Ahmad; Riyad Al-Lehebi; Alan Altraja; Peter Barker; Aaron Beastall; Andrey Belevskiy; Celine Bergeron; Leif Bjermer; Unnur Björnsdóttir; Sinthia Bosnic-Anticevich; Arnaud Bourdin; Guy Brusselle; John Busby; Giorgio Walter Canonica; Victoria Carter; Kenneth Chapman; Nicholas Chapman; George Christoff; Borja Cosio; Richard Costello; James Fingleton; João Ioa Fonseca; Mina Gaga; Peter Gibson; Susanne Hansen; Liam Heaney; Enrico Heffler; Mark Hew; Takahiko Horiguchi; Flavia Hoyte; Richard Hubbard; Takashi Iwanaga; David Jackson; Rohit Katial; Mariko Siyue Koh; Konstantinos Kostikas; Piotr Kuna; Sverre Lehmann; Lauri Lehtimäki; Renaud Louis; Dóra Lúdvíksdóttir; Njira Lugogo; Bassam Mahboub; Neil Martin; Jorge Máspero; Andrew Menzies-Gow; Arjun Mohan; Ruth Murray; Tatsuya Nagano; Nikolaos Papadopoulos; Andriana Papaioannou; Pujan Patel; Luis Perez-De-Llano; Diahn-Warng Perng; Matthew Peters; Paul Pfeffer; Paulo Márcio Pitrez; Roy Alton Pleasants; Todor Popov; Celeste Porsbjerg; Francesca Puggioni; Anna Quinton; Chin Kook Rhee; Mohsen Sadatsafavi; Sundeep Salvi; Giulia Scioscia; Chau-Chyun Sheu; Concetta Sirena; Camille Taillé; Christian Taube; Carlos Torres-Duque; Ming-Ju Tsai; Alf Tunsäter; Charlotte Suppli Ulrik; David Price

doi:10.1016/j.jaip.2025.08.021

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Response to biologics along a gradient of T2 involvement in patients with severe asthma: a data-driven biomarker clustering approach

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Response to biologics along a gradient of T2 involvement in patients with severe asthma: a data-driven biomarker clustering approach

Eileen Wang, William Henley, Désirée Larenas-Linnemann, Lakmini Bulathsinhala, Trung Tran, Michael Wechsler, Shawn Aaron, Mona Al-Ahmad, Riyad Al-Lehebi, Alan Altraja, …

Journal of Allergy and Clinical Immunology: In Practice

09/2025

DOI: https://doi.org/10.1016/j.jaip.2025.08.021

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Title: Response to biologics along a gradient of T2 involvement in patients with severe asthma: a data-driven biomarker clustering approach
Creators - without role: Eileen Wang - National Jewish Health
William Henley - Observational & Pragmatic Research Institute
Désirée Larenas-Linnemann - Hospital Médica Sur
Lakmini Bulathsinhala - Observational & Pragmatic Research Institute
Trung Tran - AstraZeneca
Michael Wechsler - National Jewish Health
Shawn Aaron - Ottawa Hospital
Mona Al-Ahmad - Ministry of Health
Riyad Al-Lehebi - Alfaisal University
Alan Altraja - Tartu University Hospital
Peter Barker - AstraZeneca
Aaron Beastall - Observational & Pragmatic Research Institute
Andrey Belevskiy
Celine Bergeron - Vancouver General Hospital
Leif Bjermer - Skåne University Hospital
Unnur Björnsdóttir - Reykjavík University
Sinthia Bosnic-Anticevich - Woolcock Institute of Medical Research
Arnaud Bourdin - Université de Montpellier, Physiologie et Médecine Expérimentale du coeur et des muscles - PhyMedExp
Guy Brusselle - Erasmus MC
John Busby - Queen's University Belfast
Giorgio Walter Canonica - Humanitas University
Victoria Carter - Observational & Pragmatic Research Institute
Kenneth Chapman - University of Toronto
Nicholas Chapman - National Jewish Health
George Christoff
Borja Cosio - Health Research Institute of the Balearic Islands
Richard Costello - Beaumont Hospital
James Fingleton - Capital and Coast District Health Board
João Ioa Fonseca
Mina Gaga - Hygeia Hospital
Peter Gibson - John Hunter Hospital
Susanne Hansen - Frederiksberg Hospital
Liam Heaney - Queen's University Belfast
Enrico Heffler - IRCCS Humanitas Research Hospital
Mark Hew - Alfred Health
Takahiko Horiguchi
Flavia Hoyte - University of Colorado Denver
Richard Hubbard - Observational & Pragmatic Research Institute
Takashi Iwanaga - Kindai University Hospital
David Jackson - King's College London
Rohit Katial - University of Colorado Denver
Mariko Siyue Koh - Singapore General Hospital
Konstantinos Kostikas
Piotr Kuna - Medical University of Lodz
Sverre Lehmann - Haukeland University Hospital
Lauri Lehtimäki - Tampere University
Renaud Louis - University of Liège
Dóra Lúdvíksdóttir
Njira Lugogo - University of Michigan
Bassam Mahboub - Dubai Health Authority
Neil Martin - University of Leicester
Jorge Máspero - Favaloro Foundation
Andrew Menzies-Gow - Harefield Hospital
Arjun Mohan - University of Michigan
Ruth Murray
Tatsuya Nagano - Kobe University
Nikolaos Papadopoulos - University of Manchester
Andriana Papaioannou - National and Kapodistrian University of Athens
Pujan Patel - Royal Brompton Hospital
Luis Perez-De-Llano
Diahn-Warng Perng
Matthew Peters - Concord Repatriation General Hospital
Paul Pfeffer - Barts Health NHS Trust
Paulo Márcio Pitrez - Santa Casa Hospital
Roy Alton Pleasants - Lung Institute
Todor Popov - University Hospital St. Ivan Rilski
Celeste Porsbjerg - Bispebjerg Hospital
Francesca Puggioni - IRCCS Humanitas Research Hospital
Anna Quinton - AstraZeneca
Chin Kook Rhee - Catholic University of Korea
Mohsen Sadatsafavi - University of British Columbia
Sundeep Salvi
Giulia Scioscia - University of Foggia
Chau-Chyun Sheu
Concetta Sirena
Camille Taillé - Université Paris Cité
Christian Taube - Ruhrlandklinik
Carlos Torres-Duque - Fundación Neumológica Colombiana
Ming-Ju Tsai
Alf Tunsäter - Skåne University Hospital
Charlotte Suppli Ulrik - Copenhagen University Hospital
David Price - Observational & Pragmatic Research Institute
Publication Details: Journal of Allergy and Clinical Immunology: In Practice
Identifiers: 99106640709311
Academic Unit: Physiologie et Médecine Expérimentale du coeur et des muscles - PhyMedExp
Language: English
Resource Type: Journal article
Local Fields: hal-05252162