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Real-time assessment of adherence to antiretroviral drugs: a moving target
Article de revue scientifique   Avec comité de lecture

Real-time assessment of adherence to antiretroviral drugs: a moving target

Vincent Le-Moing
AIDS. Official journal of the international AIDS Society, Vol.36(7), p.1045-1046
01/06/2022
PMID: 35652675

Résumé

Anti-HIV Agents Anti-Retroviral Agents HIV Infections Humans
The relationship between adherence and virological response to antiretroviral drugs in people with HIV (PWH) appears quite trivial at first look. Suboptimal adherence leads to lack of control of viremia or rebound of previously undetectable plasma HIV viral load and secondarily to resistance, durable failure, notwithstanding the ecological risk of persistent transmission of more and more resistant strains. In cohort studies, impact of nonadherence on virological response has been demonstrated by many studies both in low and high-resources settings [...].On a practical point of view, measuring adherence is more challenging [...]. Jennings et al.[8] present the results of a prospectiveobservational study conducted in South Africa [...].

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