Abstract
We describe the predictive value of BRCA1 gene status on trabectedin efficacy and found no correlation despite the mechanisms of action of this drug that rely on DNA repair systems.
- Title
- Prospective assessment of the predictive value of the BRCA1 gene status in sarcoma patients treated with trabectedin: an updated analysis of the EORTC 62091 trial
- Creators - without role
- Antoine Italiano - InsermNathan Touati - European Organisation for Research and Treatment of CancerSaskia Litière - European Organisation for Research and Treatment of CancerFrançoise Collin - Centre Georges François LeclercPhilippe Pourquier - Université de Montpellier, Institut de Recherche en Cancérologie de Montpellier - IRCMAlessandro Gronchi - Tumori Foundation
- Publication Details
- Cancer Medicine, Vol.7(5), pp.1575-1577
- Identifiers
- 9947382609311
- Academic Unit
- Institut de Recherche en Cancérologie de Montpellier - IRCM
- Language
- English
- Resource Type
- Journal article
- Local Fields
- hal-02289349