Logo image
Se connecter
Preparation of anti-1,2-Disubstituted Homopropargylic Alcohols by Addition of Allenyl(cyano)cuprates to Aldehydes
Article de revue   Avec comité de lecture

Preparation of anti-1,2-Disubstituted Homopropargylic Alcohols by Addition of Allenyl(cyano)cuprates to Aldehydes

Nacira Alouane, Emmanuel Vrancken et Pierre Mangeney
Synthesis (Stuttgart), Vol.2007(8), pp.1261-1264
18/04/2007

Résumé

Chemical Sciences Organic chemistry
The generality of the addition of allenyl(cyano)cuprates to aldehydes to afford anti-1,2-disubstituted homopropargylic alcohols was studied. The reaction is general, regardless of the nature of the cyanocuprate, although with alkyl-substituted derivatives the anti selectivity is dependent upon the nature of the aldehyde.

Indicateurs

1 Consultations de la notice

Détails

Logo image