Abstract
In this study, we describe the synthesis of 1,4-disustituted-1,2,3-triazolo-ribonucleosides by means of 1,3-dipolar cycloaddition between various N-1 propargyl-pyrimidines and 1'-azido2',3',5'-tri-O-benzoylribose catalyzed by Na2CuP2O7/sodium ascorbate. All obtained compounds were evaluated for their anti-HCV activity in vitro.