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Prediction of HIV Drug Resistance Based on Virologic, Immunologic, Clinical, and/or Adherence Criteria in the Stratall ANRS 12110/ESTHER Trial in Cameroon
Article de revue   Avec comité de lecture

Prediction of HIV Drug Resistance Based on Virologic, Immunologic, Clinical, and/or Adherence Criteria in the Stratall ANRS 12110/ESTHER Trial in Cameroon

Charlotte Boullé, Charles Kouanfack, Gabrièle Laborde-Balen, Avelin Aghokeng Fobang, Sylvie Boyer, Maria Carrieri, Serge Kaze, Jean-Marc Mben, Marlise Dontsop, Bruno Spire, …
Clinical infectious diseases, Vol.57(4), pp.604-607
15/08/2013
PMID: 23667264

Résumé

Adult Anti-HIV Agents Assessment of Medication Adherence Cameroon CD4 Lymphocyte Count Decision Support Techniques Drug Resistance, Viral Female HIV Infections Hospitals Human health and pathology Humans Life Sciences Male Middle Aged Rural Population Viral Load
Our study in Cameroonian rural district hospitals showed that the immunologic and clinical failure criteria had poor performance to identify human immunodeficiency virus drug resistance in a timely manner. Switching to second-line antiretroviral therapy after 2 consecutive viral loads ≥5000 copies/mL, as recommended by the World Health Organization, appeared to be the most appropriate strategy.

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