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Photoinduced Free-Radical Preparation of Bis-Phosphonates and Bis-Phosphinates from Alkynes
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Photoinduced Free-Radical Preparation of Bis-Phosphonates and Bis-Phosphinates from Alkynes

Florian Vasco, Ilyana Gonzales, Beatrice Roy, Jean-pierre Uttaro et Suzanne Peyrottes
European journal of organic chemistry
02/12/2025

Résumé

Chemistry Chemistry, Organic Physical Sciences Science & Technology
A one-pot access to alkyl-bisphosphonates and alkyl-bisphosphinates was developed using affordable starting materials (terminal alkynes and low-cost photoinitiator), no metal catalyst, neither ligand, and no or little amounts of solvents. The radical reaction proceeded smoothly under UV exposure, the reaction conditions were optimized and the scope of the reaction was explored.

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