Pediatric antiphospholipid syndrome: is it the same as an adult?

Viсtoria Bitsadze; Jamilya Khizroeva; Arina Lazarchuk; Polina Salnikova; Fidan Yagubova; Maria Tretyakova; Kristina Grigoreva; Nilufar Gashimova; Valentina Tsibizova; Anna Karpova; Aleksei Mostovoi; Daredzhan Kapanadze; Olga Voskresenskaya; Svetlana Akinshina; Gian Carlo Di Renzo; Jean-Christophe Gris; Ismail Elalamy; Alexander Makatsariya

doi:10.1080/14767058.2024.2390637

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Pediatric antiphospholipid syndrome: is it the same as an adult?

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Pediatric antiphospholipid syndrome: is it the same as an adult?

Viсtoria Bitsadze, Jamilya Khizroeva, Arina Lazarchuk, Polina Salnikova, Fidan Yagubova, Maria Tretyakova, Kristina Grigoreva, Nilufar Gashimova, Valentina Tsibizova, Anna Karpova, …

The journal of maternal-fetal & neonatal medicine, Vol.37(1), p.2390637

12/2024

DOI: https://doi.org/10.1080/14767058.2024.2390637

PMID: 39155241

Résumé

Adult

Antiphospholipid Syndrome - complications

Antiphospholipid Syndrome - diagnosis

Antiphospholipid Syndrome - therapy

Child

Humans

Infant, Newborn

Thrombophilia - complications

Thrombophilia - diagnosis

Thrombophilia - etiology

Antiphospholipid syndrome in neonates and children is a rare, but in some cases life-threatening condition with arterial and/or venous thrombosis and/or non-thrombotic neurological, skin, ophthalmological and other manifestations. This review highlights the available information about the features of pediatric APS, including the rare catastrophic form, the differences between pediatric and adult APS, and the role of genetic thrombophilia in APS manifestation. The clinical manifestations and treatment options for APS in children may differ from those in adults, and prescribing therapy can be challenging due to the unique clinical and morphological characteristics of the pediatric patient. Pediatric APS may be a predictor of the development of certain autoimmune diseases and classic manifestations of APS in adulthood, therefore, a revision of the existing criteria for the diagnosis and treatment of APS in children is necessary.

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Détails

Titre: Pediatric antiphospholipid syndrome: is it the same as an adult?
Créateurs - sans rôle: Viсtoria Bitsadze - Department of Obstetrics, Gynecology and Perinatal Medicine, N. F. Filatov Clinical Institute of Children's Health, I. M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia
Jamilya Khizroeva - Department of Obstetrics, Gynecology and Perinatal Medicine, N. F. Filatov Clinical Institute of Children's Health, I. M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia
Arina Lazarchuk - Department of Obstetrics, Gynecology and Perinatal Medicine, N. F. Filatov Clinical Institute of Children's Health, I. M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia
Polina Salnikova - Department of Obstetrics, Gynecology and Perinatal Medicine, N. F. Filatov Clinical Institute of Children's Health, I. M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia
Fidan Yagubova - Department of Obstetrics, Gynecology and Perinatal Medicine, N. F. Filatov Clinical Institute of Children's Health, I. M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia
Maria Tretyakova - Department of Obstetrics, Gynecology and Perinatal Medicine, N. F. Filatov Clinical Institute of Children's Health, I. M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia
Kristina Grigoreva - Department of Obstetrics, Gynecology and Perinatal Medicine, N. F. Filatov Clinical Institute of Children's Health, I. M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia
Nilufar Gashimova - Department of Obstetrics, Gynecology and Perinatal Medicine, N. F. Filatov Clinical Institute of Children's Health, I. M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia
Valentina Tsibizova - The PREIS School (International and European School of Perinatal, Neonatal and Reproductive Medicine), Firenze, Italy
Anna Karpova - Health Ministry of Russian Federation, Yaroslavl State Medical University, Yaroslavl, Russia
Aleksei Mostovoi - Health Ministry of Russian Federation, Yaroslavl State Medical University, Yaroslavl, Russia
Daredzhan Kapanadze - Center of Pathology of Pregnancy and Hemostasis «Medlabi», Tbilisi, Georgia
Olga Voskresenskaya - Department of Nervous Diseases and Neurosurgery, N.V. Sklifosovsky Institute of Clinical Medicine, I. M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia
Svetlana Akinshina - Department of Obstetrics, Gynecology and Perinatal Medicine, N. F. Filatov Clinical Institute of Children's Health, I. M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia
Gian Carlo Di Renzo - The PREIS School (International and European School of Perinatal, Neonatal and Reproductive Medicine), Firenze, Italy
Jean-Christophe Gris - Faculty of Pharmaceutical and Biological Sciences, Montpellier University, Montpellier, France
Ismail Elalamy - Hospital Tenon, Paris, France
Alexander Makatsariya - Department of Obstetrics, Gynecology and Perinatal Medicine, N. F. Filatov Clinical Institute of Children's Health, I. M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia
Détails de publication: The journal of maternal-fetal & neonatal medicine, Vol.37(1), p.2390637
Identifiants: 99139052509311
Unité académique: Institut Desbrest d Epidemiologie et de Sante Publique - IDESP
Langue: English
Type de ressource: Journal article