Logo image
Palestinian infantile visceral leishmaniasis caused by a genetic variant of Leishmania infantum belonging to a new zymodeme
Article de revue scientifique   Avec comité de lecture

Palestinian infantile visceral leishmaniasis caused by a genetic variant of Leishmania infantum belonging to a new zymodeme

Khaldoun A Bader, Lionel F Schnur, Abedelmajeed Nasereddin, Francine Pratlong, Jean-Pierre Dedet, Loay Shaheen, Obaida Yousef et Charles L Greenblatt
Tropical medicine & international health, Vol.10(6), p.618-620
06/2005
PMID: 15941427

Résumé

Animals Child, Preschool Disease Reservoirs - veterinary DNA, Protozoan - analysis Dog Diseases - parasitology Dogs Humans Leishmania infantum - genetics Leishmaniasis, Visceral - genetics Leishmaniasis, Visceral - parasitology Male Polymerase Chain Reaction - methods Polymorphism, Restriction Fragment Length
The parasites causing a Palestinian case of infantile visceral leishmaniasis (IVL) and those from four dogs from the Jenin District were identified serologically, biochemically and molecular biologically as Leishmania infantum, showing dogs act as a reservoir. The strain from the human case was distinct because of its unique 200-bp kDNA-polymerase chain reaction (PCR) component in its restriction fragment length polymorphism (RFLP) profile after digestion with the endonuclease RsaI, and by the electrophoretic mobility of its malate dehydrogenase (MDH(140)), designating it the reference strain of a new zymodeme of L. infantum, MON-281.

Indicateurs

1 Consultations de la notice

Détails

Logo image