POFA trial study protocol: a multicentre, double-blind, randomised, controlled clinical trial comparing opioid-free versus opioid anaesthesia on postoperative opioid-related adverse events after major or intermediate non-cardiac surgery

Hélène Beloeil; Bruno Laviolle; Cédric Ménard; Catherine Paugam-Burtz; Matthias Garot; Karim Asehnoune; Vincent Minville; Philippe Cuvillon; Sebastien Oger; Julien Nadaud; Sylvain Lecoeur; Gerald Chanques; Emmanuel Futier

doi:10.1136/bmjopen-2017-020873

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POFA trial study protocol: a multicentre, double-blind, randomised, controlled clinical trial comparing opioid-free versus opioid anaesthesia on postoperative opioid-related adverse events after major or intermediate non-cardiac surgery

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POFA trial study protocol: a multicentre, double-blind, randomised, controlled clinical trial comparing opioid-free versus opioid anaesthesia on postoperative opioid-related adverse events after major or intermediate non-cardiac surgery

Hélène Beloeil, Bruno Laviolle, Cédric Ménard, Catherine Paugam-Burtz, Matthias Garot, Karim Asehnoune, Vincent Minville, Philippe Cuvillon, Sebastien Oger, Julien Nadaud, …

BMJ Open, Vol.8(6)

06/2018

DOI: https://doi.org/10.1136/bmjopen-2017-020873

PMID: 29961015

Abstract

opioid

remifentanil

opioid-free anesthesia

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Title: POFA trial study protocol: a multicentre, double-blind, randomised, controlled clinical trial comparing opioid-free versus opioid anaesthesia on postoperative opioid-related adverse events after major or intermediate non-cardiac surgery
Creators - without role: Hélène Beloeil - Université de Rennes
Bruno Laviolle - Centre Hospitalier Universitaire de Rennes
Cédric Ménard - Centre Hospitalier Universitaire de Rennes
Catherine Paugam-Burtz - Hôpital Beaujon
Matthias Garot - Centre Hospitalier Universitaire de Lille
Karim Asehnoune - Centre Hospitalier Universitaire de Nantes
Vincent Minville - Centre Hospitalier Universitaire de Toulouse
Philippe Cuvillon - Université de Montpellier, Initial MAnagement & prevent of acute orGan failures IN critically ill patiEnts - IMAGINE
Sebastien Oger - Hopital de Périgueux
Julien Nadaud - Centre Hospitalier Régional de Metz-Thionville
Sylvain Lecoeur - Yves Rocher
Gerald Chanques - Centre Hospitalier Universitaire de Montpellier
Emmanuel Futier - Genetique Reproduction and Developpement
Publication Details: BMJ Open, Vol.8(6)
Grant note: French Ministry of Health
Identifiers: 9947197009311
Academic Unit: Physiologie et Médecine Expérimentale du coeur et des muscles - PhyMedExp; Initial MAnagement & prevent of acute orGan failures IN critically ill patiEnts - IMAGINE
Language: English
Resource Type: Journal article
Local Fields: hal-01827634