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Oxyfold: A simple and efficient solid-supported reagent for disulfide bond formation
Article de revue scientifique

Oxyfold: A simple and efficient solid-supported reagent for disulfide bond formation

P. Verdié, Luisa Ronga, M. Cristau, M. Amblard, S. Cantel, C. Enjalbal, K. Puget, J. Martinez et G. Subra
Chemistry - An Asian Journal, Vol.6(9), p.2382-2389
2011

Résumé

The synthesis and use of novel polymer-supported reagents for disulfide bond formation is described. This family of supported reagents consists of a series of oxidized methionines grafted onto a solid support. Their cost and the simplicity of their preparation through N-carboxyanhydride polymerization on beads make them reactants of choice for the formation of disulfide bridges in peptides. Copyright © 2011 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

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