Ovarian and peritoneal psammocarcinoma: Results of a multicenter study on 25 patients

Jean-Baptiste Delhorme; Jordan Ohayon; Sébastien Gouy; Gerlinde Averous; Catherine Genestie; Léopold Gaichies; Olivier Glehen; Jean-Marc Guilloit; Denis Pezet; Francois Quenet; Gwenaël Ferron; Cécile Brigand; Philippe Morice; Charles Honoré; Julio Abba; Karine Abboud; Mohammad Alyami; Catherine Arvieux; Naoual Bakrin; Gisèle Balagué; Vincent Barrau; Houda Ben Rejeb; Jean-Marc Bereder; Isabelle Berton-Rigaud; Frédéric Bibeau; Isabelle Bonnefoy; Dominique Bouzard; Ivan Bricault; Sébastien Carrère; Cécile de Chaisemartin; Madleen Chassang; Anne Chevallier; Thomas Courvoisier; Peggy Dartigues; Anthony Dohan; Julien Dubreuil; Frédéric Dumont; Clarisse Eveno; Marie Faruch-Bilfeld; Juliette Fontaine; Laure Fournier; Johan Gagniere; Delphine Geffroy; Laurent Ghouti; François-Noël Gilly; Laurence Gladieff; Diane Goéré; Aymeric Guibal; Frédéric Guyon; Bruno Heyd; Christine Hoeffel; Constance Hordonneau; Sylvie Isaac; Peggy Jourdan-Enfer; Rachid Kaci; Reza Kianmanesh; Catherine Labbé-Devilliers; Joëlle Lacroix; Bernard Lelong; Agnès Leroux-Broussier; Yoann Lherm; Réa Lo Dico; Gérard Lorimier; Caroline Malhaire; Frédéric Marchal; Pascale Mariani; Emilie Mathiotte; Pierre Meeus; Eliane Mery; Simon Msika; Cédric Nadeau; Pablo Ortega-Deballon; Guillaume Passot; Olivier Pellet; Patrice Peyrat; Nicolas Pirro; Marc Pocard; Flora Poizat; Jack Porcheron; Anaïs Poulet; François Quenet; Patrick Rat; Pierre Rousselot; Pascal Rousset; Hélène Senellart; Martine Serrano; Vincent Servois; Olivia Sgabura; Andrea Skanjeti; Magali Svrcek; Raphaël Tetreau; Emilie Thibaudeau; Yann Touchefeu; Jean-Jacques Tuech; Séverine Valmary-Degano; Delphine Vaudoyer; Stéphane Velasco; Véronique Verriele-Beurrier; Laurent Villeneuve; Romuald Wernert; Franck Zinzindohoue; French Network for Rare Peritoneal Malignancies (RENAPE)

doi:10.1016/j.ejso.2019.12.005

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Ovarian and peritoneal psammocarcinoma: Results of a multicenter study on 25 patients

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Ovarian and peritoneal psammocarcinoma: Results of a multicenter study on 25 patients

Jean-Baptiste Delhorme, Jordan Ohayon, Sébastien Gouy, Gerlinde Averous, Catherine Genestie, Léopold Gaichies, Olivier Glehen, Jean-Marc Guilloit, Denis Pezet, Francois Quenet, …

European journal of surgical oncology, Vol.46(5), pp.862-867

05/2020

DOI: https://doi.org/10.1016/j.ejso.2019.12.005

PMID: 31902591

Résumé

Intraperitoneal chemotherapy

Ovary

Peritoneum

Psammocarcinoma

Surgery

Psammocarcinoma (PK) is a rare disease of unknown origin. We aimed to report the characteristics, management and survival of patients operated on for PK within the French Network for Rare Peritoneal Malignancies (RENAPE) expert centers. All consecutive cases of PK operated within all 26 RENAPE centers between 1997 and 2018 were retrospectively analyzed. Twenty-five patients were identified. The median age was 53 years [range 17–78]. None of the patients had extra peritoneal metastases at diagnosis. A median of 6 cycles of carboplatin-based systemic chemotherapy was delivered in 52% preoperatively (n = 13) and 56% postoperatively (n = 14); associated with placlitaxel for 12 patients. All patients were operated on. The median PCI was 23 [0–33]. Eighty-four percent had a complete cytoreductive surgery through digestive (n = 7), spleen (n = 3), pancreas (n = 1) resections and/or multiple peritonectomies (n = 11). Five patients (20%) had intraperitoneal chemotherapy. Morbidity (Dindo-Clavien ≥3) was 12%. No postoperative death occurred. After a median follow-up of 42 months (range [2–194]), the median overall (OS) and progression-free (DFS) survival times were respectively 128 months and 31 months. Eighteen patients recurred (72%), mainly in the peritoneum (n = 16). Four of them (22%) were reoperated. The 5 and 10-year DFS rates were both 20.3%. The 5 and 10-year OS rates were 62% and 51.7%, respectively. A complete cytoreductive surgery was associated with a better OS and DFS in a univariate analysis. Complete cytoreductive surgery is the cornerstone of the PK's management as a primary treatment. Recurrence remains common and new adjuvant strategies seem needed.

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Titre: Ovarian and peritoneal psammocarcinoma: Results of a multicenter study on 25 patients
Créateurs - sans rôle: Jean-Baptiste Delhorme - Department of Surgical Oncology, Gustave Roussy Cancer Campus, 114, rue Edouard vaillant, 94800, Villejuif, France
Jordan Ohayon - Department of Surgical Oncology, Gustave Roussy Cancer Campus, 114, rue Edouard vaillant, 94800, Villejuif, France
Sébastien Gouy - Department of Gynecologic Surgery, Gustave Roussy Cancer Campus, 114, rue Edouard vaillant, 94800, Villejuif, France
Gerlinde Averous - Department of Pathology, Hautepierre Hospital, Strasbourg University Hospital, 1 avenue Molière, 67200, Strasbourg, France
Catherine Genestie - Department of Pathology, Gustave Roussy Cancer Campus, 114, rue Edouard vaillant, 94800, Villejuif, France
Léopold Gaichies - Department of Gynecologic Surgery, Gustave Roussy Cancer Campus, 114, rue Edouard vaillant, 94800, Villejuif, France
Olivier Glehen - Hospices Civils de Lyon
Jean-Marc Guilloit - Department of Surgical Oncology, François Baclesse Institute, 3 avenue du general Harris, 14000, Caen, France
Denis Pezet - Department of Digestive Surgery, Clermont-Ferrand University Hospital, 1 rue Lucie et Raymond Aubrac, 63100, Clermont-Ferrand, France
Francois Quenet - Department of Surgical Oncology, Montpellier Cancer Center, 208 avenue des apothicaires, 34298, Montpellier, France
Gwenaël Ferron - Department of Surgical Oncology, Claudius Regaud Insitute, 20-24 rue du pont Saint-Pierre, 31300, Toulouse, France
Cécile Brigand - Department of General and Digestive Surgery, Hautepierre Hospital, Strasbourg University Hospital, 1 avenue Molière, 67200, Strasbourg, France
Philippe Morice - Department of Gynecologic Surgery, Gustave Roussy Cancer Campus, 114, rue Edouard vaillant, 94800, Villejuif, France
Charles Honoré - Department of Surgical Oncology, Gustave Roussy Cancer Campus, 114, rue Edouard vaillant, 94800, Villejuif, France
Julio Abba - Department of Digestive Surgery, Grenoble University Hospital, Grenoble, France
Karine Abboud - Department of General Surgery, CHU Hospital, Jean Monnet University, Saint Étienne, France
Mohammad Alyami - Department of Digestive Surgery, Lyon-Sud University Hospital, Lyon, France
Catherine Arvieux - Department of Digestive Surgery, Grenoble University Hospital, Grenoble, France
Gerlinde Averous - Department of Pathology, Hautepierre University Hospital, Strasbourg, France
Naoual Bakrin - Department of Digestive Surgery, Lyon-Sud University Hospital, Lyon, France
Gisèle Balagué - Department of Radiology, Claudius Regaud Institute IUTC, Toulouse, France
Vincent Barrau - Department of Radiology, Centre cardiologique du Nord, Saint Denis, France
Houda Ben Rejeb - Department of Pathology, Bergonie Institute, Bordeaux, France
Jean-Marc Bereder - Department of Digestive Surgery, Archet 2 University Hospital, Nice, France
Isabelle Berton-Rigaud - Department of Digestive Oncology, ICO René Gauducheau Cancer Center, Saint-Herblain, France
Frédéric Bibeau - Department of Pathology, Caen University Hospital, Caen, France
Isabelle Bonnefoy - Department of Digestive Surgery, Lyon-Sud University Hospital, Lyon, France
Dominique Bouzard - Department of Surgery, Louis Mourier University Hospital, Colombes, France
Ivan Bricault - Department of Radiology, Grenoble University Hospital, Grenoble, France
Cécile Brigand - Hôpitaux Universitaires de Strasbourg
Sébastien Carrère - Department of Surgical Oncology, Val d’Aurelle Montpellier Cancer Center, Montpellier, France
Cécile de Chaisemartin - Department of Surgical Oncology, Paoli Calmettes Institute, Marseille, France
Madleen Chassang - Department of Radiology, Archet 2 University Hospital, Nice, France
Anne Chevallier - Department of Pathology, Archet 2 University Hospital, Nice, France
Thomas Courvoisier - Department of Digestive Surgery, Poitiers University Hospital, Poitiers, France
Peggy Dartigues - Department of Pathology, Gustave Roussy Institute, Villejuif, France
Anthony Dohan - Department of Radiology, Lariboisière University Hospital, Paris, France
Julien Dubreuil - Department of Radiology, Lyon-Sud University Hospital, Lyon, France
Frédéric Dumont - Department of Surgical Oncology, ICO René Gauducheau Cancer Center, Saint-Herblain, France
Clarisse Eveno - Surgical Oncologic & Digestive Unit, Lariboisière University Hospital, Paris, France
Marie Faruch-Bilfeld - Department of Radiology, University Hospital of Toulouse, Toulouse, France
Gwenaël Ferron - Department of Surgical Oncology, Claudius Regaud Institute IUTC, Toulouse, France
Juliette Fontaine - Department of Pathology, Lyon-Sud University Hospital, Lyon, France
Laure Fournier - Department of Radiology, G. Pompidou European Hospital, Paris, France
Johan Gagniere - Department of Digestive Surgery, Estaing University Hospital, Clermont-Ferrand, France
Delphine Geffroy - Department of Radiology, ICO René Gauducheau Cancer Center, Saint-Herblain, France
Laurent Ghouti - Department of Digestive Surgery, Purpan University Hospital, Toulouse, France
François-Noël Gilly - Department of Digestive Surgery, Lyon-Sud University Hospital, Lyon, France
Laurence Gladieff - Department of Medical Oncology, Claudius Regaud Institute IUTC, Toulouse, France
Olivier Glehen - Department of Digestive Surgery, Lyon-Sud University Hospital, Lyon, France
Diane Goéré - Department of Surgical Oncology, Gustave Roussy Institute, Villejuif, France
Aymeric Guibal - Department of Radiology, Hospital of Perpignan, Perpignan, France
Jean-Marc Guilloit - Department of Surgical Oncology, Francois Baclesse Comprehensive Cancer Center, Caen, France
Frédéric Guyon - Department of Surgical Oncology, Bergonie Institute, Bordeaux, France
Bruno Heyd - Department of Digestive Surgery, Minjoz University Hospital, Besançon, France
Christine Hoeffel - Department of Radiology, Robert Debré University Hospital, Reims, France
Constance Hordonneau - Department of Radiology, Montpied University Hospital, Clermont-Ferrand, France
Sylvie Isaac - Department of Pathology, Lyon-Sud University Hospital, Lyon, France
Peggy Jourdan-Enfer - Department of Digestive Surgery, Lyon-Sud University Hospital, Lyon, France
Rachid Kaci - Department of Pathology, Lariboisière University Hospital, Paris, France
Reza Kianmanesh - Department of Digestive Surgery, Robert Debré University Hospital, Reims, France
Catherine Labbé-Devilliers - Department of Radiology, ICO René Gauducheau Cancer Center, Saint-Herblain, France
Joëlle Lacroix - Department of Radiology, Francois Baclesse Comprehensive Cancer Center, Caen, France
Bernard Lelong - Department of Surgical Oncology, Paoli Calmettes Institute, Marseille, France
Agnès Leroux-Broussier - Department of Pathology, Lorraine Institute of Oncology, Vandoeuvre-les-Nancy, France
Yoann Lherm - Hospices Civils de Lyon, Pôle Information Médicale Evaluation Recherche, Unité de Recherche Clinique, Lyon, France
Réa Lo Dico - Surgical Oncologic & Digestive Unit, Lariboisière University Hospital, Paris, France
Gérard Lorimier - Department of Digestive Surgery, Angers University Hospital, Angers, France
Caroline Malhaire - Department of Radiology, Curie Institute, Paris, France
Frédéric Marchal - Université de Lorraine
Pascale Mariani - Department of Surgical Oncology, Curie Institute, Paris, France
Emilie Mathiotte - Hospices Civils de Lyon, Pôle Information Médicale Evaluation Recherche, Unité de Recherche Clinique, Lyon, France
Pierre Meeus - Centre de Recherche en Cancérologie de Lyon
Eliane Mery - Department of Pathology, Claudius Regaud Institute IUTC, Toulouse, France
Simon Msika - Department of Surgery, Louis Mourier University Hospital, Colombes, France
Cédric Nadeau - Gynaecology and Obstetrics Ward, Mother and Child Pole, Poitiers University Hospital, University of Poitiers, Poitiers, France
Pablo Ortega-Deballon - Department of Digestive Surgical Oncology, University Hospital of Dijon, Dijon, France
Guillaume Passot - Department of Digestive Surgery, Lyon-Sud University Hospital, Lyon, France
Olivier Pellet - INOLA, Lyon, France
Patrice Peyrat - Centre de Recherche en Cancérologie de Lyon
Denis Pezet - Department of Digestive Surgery, Estaing University Hospital, Clermont-Ferrand, France
Nicolas Pirro - Department of Digestive Surgery, Timône University Hospital, Marseille, France
Marc Pocard - Surgical Oncologic & Digestive Unit, Lariboisière University Hospital, Paris, France
Flora Poizat - Department of Pathology, Paoli Calmettes Institute, Marseille, France
Jack Porcheron - Department of Digestive Surgery, St Etienne University Hospital, St Etienne, France
Anaïs Poulet - Department of Digestive Surgery, Lyon-Sud University Hospital, Lyon, France
François Quenet - Department of Surgical Oncology, Val d’Aurelle Montpellier Cancer Center, Montpellier, France
Patrick Rat - Department of Digestive Surgical Oncology, University Hospital of Dijon, Dijon, France
Pierre Rousselot - Department of Pathology, Francois Baclesse Comprehensive Cancer Center, Caen, France
Pascal Rousset - Department of Radiology, Lyon-Sud University Hospital, Lyon, France
Hélène Senellart - Department of Medical Oncology, ICO René Gauducheau Cancer Center, Saint-Herblain, France
Martine Serrano - Department of Digestive Surgery, Lyon-Sud University Hospital, Lyon, France
Vincent Servois - Department of Radiology, Curie Institute, Paris, France
Olivia Sgabura - Department of Surgical Oncology, Val d’Aurelle Montpellier Cancer Center, Montpellier, France
Andrea Skanjeti - Department of Radiology, Lyon-Sud University Hospital, Lyon, France
Magali Svrcek - Assistance Publique – Hôpitaux de Paris
Raphaël Tetreau - Department of Radiology, Val d’Aurelle Montpellier Cancer Center, Montpellier, France
Emilie Thibaudeau - Department of Surgical Oncology, ICO René Gauducheau Cancer Center, Saint-Herblain, France
Yann Touchefeu - Department of Gastroenterology, Nantes University Hospital, Nantes, France
Jean-Jacques Tuech - Department of Digestive Surgery, Charles Nicolle University Hospital, Rouen, France
Séverine Valmary-Degano - Department of Pathology, Minjoz University Hospital, Besançon, France
Delphine Vaudoyer - Department of Digestive Surgery, Lyon-Sud University Hospital, Lyon, France
Stéphane Velasco - Department of Radiology, Poitiers University Hospital, Poitiers, France
Véronique Verriele-Beurrier - Department of Pathology, ICO Paul Papin Cancer Center, Angers, France
Laurent Villeneuve - Hospices Civils de Lyon
Romuald Wernert - Department of Surgical Oncology, ICO Paul Papin Cancer Center, Angers, France
Franck Zinzindohoue - Department of Digestive and General Surgery, G. Pompidou European Hospital, Paris, France
French Network for Rare Peritoneal Malignancies (RENAPE)
Détails de publication: European journal of surgical oncology, Vol.46(5), pp.862-867
Éditeur: Elsevier Ltd
Nombre de pages: 6
Identifiants: 99162927409311
Unité académique: Institut de Recherche en Cancérologie de Montpellier - IRCM
Langue: English
Type de ressource: Journal article