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Outbreak of carbapenem-resistant Acinetobacter baumannii producing the carbapenemase OXA-23 in a tertiary care hospital of Papeete, French Polynesia
Article de revue   Avec comité de lecture

Outbreak of carbapenem-resistant Acinetobacter baumannii producing the carbapenemase OXA-23 in a tertiary care hospital of Papeete, French Polynesia

Thierry Naas, Marc Levy, Claire Hirschauer, Hélène Marchandin et Patrice Nordmann
Journal of clinical microbiology, Vol.43(9), pp.4826-4829
01/09/2005
DOI: https://doi.org/10.1128/JCM.43.9.4826-4829.2005
PMID: 16145150

Résumé

Acinetobacter baumannii - drug effects Acinetobacter baumannii - enzymology Acinetobacter baumannii - genetics Acinetobacter baumannii - isolation & purification Acinetobacter Infections - epidemiology Acinetobacter Infections - microbiology Adolescent Adult Aged Aged, 80 and over Anti-Bacterial Agents - pharmacology Bacterial Proteins - genetics Bacterial Proteins - metabolism beta-Lactam Resistance beta-Lactamases - genetics beta-Lactamases - metabolism Carbapenems - pharmacology Child Disease Outbreaks Female Hospital Bed Capacity, 300 to 499 Hospitals Humans Male Microbial Sensitivity Tests Middle Aged Polynesia - epidemiology
Carbapenem-resistant Acinetobacter baumannii isolates were obtained from 24 patients between March and May 2004 at the Centre Hospitalier de Polynésie Française, Tahiti, French Polynesia. The isolates were multidrug resistant, produced the carbapenemase OXA-23, and belonged to a single clone presenting several subtypes, suggesting an endemic situation. This study further illustrates the global spread of this kind of beta-lactamase-mediated resistance.

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