Oral Glucocorticoid-Sparing Effect of Benralizumab in Severe Asthma

Parameswaran Nair; Sally Wenzel; Klaus F. Rabe; Arnaud Bourdin; Njira L. Lugogo; Piotr Kuna; Peter Barker; Stephanie Sproule; Sandhia Ponnarambil; Mitchell Goldman

doi:10.1056/NEJMoa1703501

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Oral Glucocorticoid-Sparing Effect of Benralizumab in Severe Asthma

Journal article

Open access

Peer reviewed

Oral Glucocorticoid-Sparing Effect of Benralizumab in Severe Asthma

Parameswaran Nair, Sally Wenzel, Klaus F. Rabe, Arnaud Bourdin, Njira L. Lugogo, Piotr Kuna, Peter Barker, Stephanie Sproule, Sandhia Ponnarambil and Mitchell Goldman

New England Journal of Medicine, Vol.376(25), pp.2448--2458

2017

DOI: https://doi.org/10.1056/NEJMoa1703501

PMID: 28530840

Abstract

Interleukin-5 Receptor alpha Subunit

Subcutaneous

Injections

Double-Blind Method

Asthma

Middle Aged

Drug

Glucocorticoids

Anti-Asthmatic Agents

Humans

Female

Male

Antibodies

Monoclonal

Humanized

Administration

Oral

Adult

Dose-Response Relationship

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Title: Oral Glucocorticoid-Sparing Effect of Benralizumab in Severe Asthma
Creators - without role: Parameswaran Nair - McMaster University
Sally Wenzel - University of Pittsburgh
Klaus F. Rabe - German Center for Lung Research
Arnaud Bourdin - Université de Montpellier, Physiologie et Médecine Expérimentale du coeur et des muscles - PhyMedExp
Njira L. Lugogo - Duke Medical Center
Piotr Kuna - Medical University of Lodz
Peter Barker - AstraZeneca
Stephanie Sproule - AstraZeneca
Sandhia Ponnarambil - AstraZeneca
Mitchell Goldman - AstraZeneca
Publication Details: New England Journal of Medicine, Vol.376(25), pp.2448--2458
Identifiers: 9943079009311
Academic Unit: Physiologie et Médecine Expérimentale du coeur et des muscles - PhyMedExp
Language: English
Resource Type: Journal article
Local Fields: hal-01761510