Noninvasive diagnosis of chronic kidney diseases using urinary proteome analysis

Justyna Siwy; Petra Zürbig; Angel Argilés; Joachim Beige; Marion Haubitz; Jan Jankowski; Bruce Julian; Peter Linde; David Marx; Harald Mischak; William Mullen; Jan Novak; Alberto Ortiz; Frederik Persson; Claudia Pontillo; Peter Rossing; Harald Rupprecht; Joost Schanstra; Antonia Vlahou; Raymond Vanholder

doi:10.1093/ndt/gfw337

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Noninvasive diagnosis of chronic kidney diseases using urinary proteome analysis

Journal article

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Noninvasive diagnosis of chronic kidney diseases using urinary proteome analysis

Justyna Siwy, Petra Zürbig, Angel Argilés, Joachim Beige, Marion Haubitz, Jan Jankowski, Bruce Julian, Peter Linde, David Marx, Harald Mischak, …

Nephrology Dialysis Transplantation, pp.2079-2089

01/12/2017

DOI: https://doi.org/10.1093/ndt/gfw337

PMCID: PMC5837301

PMID: 27984204

Abstract

biomarkers

chronic kidney disease

peptides

proteome analysis

urine

In spite of its invasive nature and risks, kidney biopsy is currently required for precise diagnosis of many chronic kidney diseases (CKDs). Here, we explored the hypothesis that analysis of the urinary proteome can discriminate different types of CKD irrespective of the underlying mechanism of disease.

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Title: Noninvasive diagnosis of chronic kidney diseases using urinary proteome analysis
Creators - without role: Justyna Siwy - Mosaiques Diagnostics and Therapeutics
Petra Zürbig - Mosaiques Diagnostics and Therapeutics
Angel Argilés - Biocommunication en Cardio-Métabolique
Joachim Beige - Martin Luther University Halle-Wittenberg
Marion Haubitz - Klinikum Fulda
Jan Jankowski - Department of Poultry Science
Bruce Julian - University of Alabama at Birmingham
Peter Linde - AbbVie
David Marx - Hôpitaux Universitaires de Strasbourg
Harald Mischak - University of Glasgow
William Mullen - University of Glasgow
Jan Novak - University of Alabama at Birmingham
Alberto Ortiz - Universidad Autónoma de Madrid
Frederik Persson - Steno Diabetes Centers
Claudia Pontillo - Charité - Universitätsmedizin Berlin
Peter Rossing - Steno Diabetes Centers
Harald Rupprecht - Bayreuth Medical Center
Joost Schanstra - Institut des Maladies Métaboliques et Cardiovasculaires
Antonia Vlahou - Academy of Athens
Raymond Vanholder - Ghent University Hospital
Publication Details: Nephrology Dialysis Transplantation, pp.2079-2089
Identifiers: 9937075509311
Academic Unit: Biocommunication en Cardio-Métabolique - BC2M
Language: English
Resource Type: Journal article
Local Fields: hal-01906007