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Mycobacterial biotin biosynthesis counters airway alkalinity
Article de revue   Avec comité de lecture

Mycobacterial biotin biosynthesis counters airway alkalinity

Wassim Daher et Laurent Kremer
Nature Microbiology, Vol.8(3), pp.369-370
16/02/2023

Résumé

Mycobacterium abscessus requires high levels of biotin biosynthesis during infection, because this vitamin enables key adaptations to the alkaline lung airway environment through fatty acid remodelling that increases fluidity of the cell envelope.

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