Multiplexed binding determination of seven glycoconjugates for Pseudomonas aeruginosa lectin I (PA-IL) using a DNA-based carbohydrate microarray.

Yann Chevolot; Jing Zhang; Albert Meyer; Alice Goudot; Sonia Rouanet; Sébastien Vidal; Gwladys Pourceau; Jean-Pierre Cloarec; Jean-Pierre Praly; Eliane Souteyrand; Jean-Jacques Vasseur; François Morvan

doi:10.1039/c1cc12428e

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Multiplexed binding determination of seven glycoconjugates for Pseudomonas aeruginosa lectin I (PA-IL) using a DNA-based carbohydrate microarray.

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Multiplexed binding determination of seven glycoconjugates for Pseudomonas aeruginosa lectin I (PA-IL) using a DNA-based carbohydrate microarray.

Yann Chevolot, Jing Zhang, Albert Meyer, Alice Goudot, Sonia Rouanet, Sébastien Vidal, Gwladys Pourceau, Jean-Pierre Cloarec, Jean-Pierre Praly, Eliane Souteyrand, …

Chemical Communications, Vol.47(31), pp.8826-8

21/08/2011

DOI: https://doi.org/10.1039/c1cc12428e

PMID: 21748147

Abstract

The binding of seven multivalent glycoconjugates displaying linear or antenna-like structures and different electronic environments were evaluated towards PA-IL on a DNA-based carbohydrate microarray. The affinity can be modulated by the charge and the topology of the galactosylated derivatives.

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Title: Multiplexed binding determination of seven glycoconjugates for Pseudomonas aeruginosa lectin I (PA-IL) using a DNA-based carbohydrate microarray.
Creators - without role: Yann Chevolot - Institut des Nanotechnologies de Lyon
Jing Zhang - École Centrale de Lyon
Albert Meyer - Université de Montpellier, Institut des Biomolécules Max Mousseron - IBMM
Alice Goudot - Institut des Nanotechnologies de Lyon
Sonia Rouanet - Université de Montpellier, Institut des Biomolécules Max Mousseron - IBMM
Sébastien Vidal - Centre National de la Recherche Scientifique
Gwladys Pourceau - Université de Montpellier, Institut des Biomolécules Max Mousseron - IBMM
Jean-Pierre Cloarec - INL - Chimie et Nanobiotechnologies
Jean-Pierre Praly - Institut de Chimie et Biochimie Moléculaires et Supramoléculaires
Eliane Souteyrand - Institut des Nanotechnologies de Lyon
Jean-Jacques Vasseur - Université de Montpellier, Institut des Biomolécules Max Mousseron - IBMM
François Morvan - Université de Montpellier, Institut des Biomolécules Max Mousseron - IBMM
Publication Details: Chemical Communications, Vol.47(31), pp.8826-8
Identifiers: 9946796009311
Academic Unit: Institut des Biomolécules Max Mousseron - IBMM
Language: English
Resource Type: Journal article
Local Fields: hal-00695908