Résumé
Introduction. - Candida infection limited to the central nervous system is extremely rare, and may be confused with tuberculosis on the grounds of the clinical and cerebrospinal fluid findings.
Case report. - A 23-year-old immunocompetent drug addict presented with alternating sciatica over a period of several months, followed by multiple cranial nerve involvement in the setting of marked weight loss. The histopathologic examination of a leptomeningeal neurosurgical biopsy was required to establish the diagnosis of neuromeningeal infection with Candida albicans.
Conclusion. - This case report underlines diagnostic difficulties of candidal meningitis and reviews current therapeutic recommendations. (C) 2010 Elsevier Masson SAS. All rights reserved.