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Mapping of the chromosome 11 breakpoint of the t(4;11)(q21;p14–15) translocation
Article de revue

Mapping of the chromosome 11 breakpoint of the t(4;11)(q21;p14–15) translocation

Vasiliki Kalatzis, Gregory B. Peters et Alexander Dobrovic
Cancer genetics and cytogenetics, Vol.69(2), pp.122-125
01/09/1993
PMID: 8402548

Résumé

We describe the localization of the chromosome 11 breakpoint of a T-ALL translocation, t(4;11)(q21;p14–15), to sub-band 11p15.5. The breakpoint is located between the genes for insulin-like growth factor II (IGFII) and the M1 subunit of ribonucleotide reductase (RRM1). This region does not include any previously cloned genes involved in cancer.

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