Malaria transmission-blocking activity in experimental infections of Anopheles gambiae from naturally infected Plasmodium falciparum gametocyte carriers

Bert Mulder; Timoléon Tchuinkam; Koen Dechering; Jan Peter Verhave; Pierre Carnevale; Joep H.E.Th Meuwissen; Vincent Robert

doi:10.1016/0035-9203(94)90534-7

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Malaria transmission-blocking activity in experimental infections of Anopheles gambiae from naturally infected Plasmodium falciparum gametocyte carriers

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Malaria transmission-blocking activity in experimental infections of Anopheles gambiae from naturally infected Plasmodium falciparum gametocyte carriers

Bert Mulder, Timoléon Tchuinkam, Koen Dechering, Jan Peter Verhave, Pierre Carnevale, Joep H.E.Th Meuwissen et Vincent Robert

Transactions of the Royal Society of Tropical Medicine and Hygiene, Vol.88(1), pp.121-125

1994

DOI: https://doi.org/10.1016/0035-9203(94)90534-7

PMID: 8153987

Résumé

Experimental infections of anopheline mosquitoes were carried out with Plasmodium falciparum gametocytes from 65 naturally infected patients in Cameroon. A comparison was made between infections with blood containing autologous plasma and blood in which the plasma was replaced with plasma from a donor without previous malaria exposure. A lower infection rate was observed in 50 of 65 autologous plasma samples. Transmission was significantly blocked in 3 infections. This indicates that, in a population living in an area endemic for malaria, blood plasma factor(s) can reduce the transmission capacity of gametocyte carriers to mosquitoes.

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Titre: Malaria transmission-blocking activity in experimental infections of Anopheles gambiae from naturally infected Plasmodium falciparum gametocyte carriers
Créateurs - sans rôle: Bert Mulder - University of Wageningen and University of Nijmegen, Department of Medical Parasitology, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands
Timoléon Tchuinkam - Medical Entomology Service, ORSTOM/OCEAC, Yaoundé, Cameroon
Koen Dechering - University of Wageningen and University of Nijmegen, Department of Medical Parasitology, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands
Jan Peter Verhave - University of Wageningen and University of Nijmegen, Department of Medical Parasitology, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands
Pierre Carnevale - Medical Entomology Service, ORSTOM/OCEAC, Yaoundé, Cameroon
Joep H.E.Th Meuwissen - University of Wageningen and University of Nijmegen, Department of Medical Parasitology, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands
Vincent Robert - Medical Entomology Service, ORSTOM/OCEAC, Yaoundé, Cameroon
Détails de publication: Transactions of the Royal Society of Tropical Medicine and Hygiene, Vol.88(1), pp.121-125
Éditeur: Elsevier Ltd
Nombre de pages: 5
Identifiants: 99158944609311
Unité académique: Maladies Infectieuses et Vecteurs : Ecologie, Génétique, Evolution et Contrôle - MIVEGEC
Langue: English
Type de ressource: Journal article