Lupus anticoagulant and ischemic strokes: about two case reports

Julie Hilaire; Clara Noizat; Minh-Toan Duong; Maxime Delrue; Dominique Herve; Alain Stepanian; Marie Neuwirth; Arezki Hadj-Ali; Berangere S. Joly; Agnes Veyradier; Virginie Siguret; Nicolas Beranger

doi:10.1684/abc.2021.1662

Retour

Lupus anticoagulant and ischemic strokes: about two case reports

Article de revue

Avec comité de lecture

Lupus anticoagulant and ischemic strokes: about two case reports

Julie Hilaire, Clara Noizat, Minh-Toan Duong, Maxime Delrue, Dominique Herve, Alain Stepanian, Marie Neuwirth, Arezki Hadj-Ali, Berangere S. Joly, Agnes Veyradier, …

Annales de biologie clinique (Paris), Vol.79(4), pp.361-367

01/08/2021

DOI: https://doi.org/10.1684/abc.2021.1662

PMID: 34427558

Résumé

Life Sciences & Biomedicine

Medical Laboratory Technology

Medicine, Research & Experimental

Research & Experimental Medicine

Science & Technology

Antiphospholipid syndrome (APS) is an autoimmune disease characterized by thrombotic clinical manifestations, including ischemic stroke. Testing for lupus anticoagulant (LA) among antiphospholipid antibodies is key to the diagnosis of antiphospholipid syndrome (APS). Given the impact on patient management, close clinician-pathologist collaboration is crucial for the presence of LA in a thrombotic setting. Testing for LA must be carried out using specific and appropriate clotting assays and the pathologist should be aware of interferences. We report here two cases of stroke associated with the presence of LA, and recall the strategy for screening for LA.

Indicateurs

1 Consultations de la notice

Détails

Titre: Lupus anticoagulant and ischemic strokes: about two case reports
Créateurs - sans rôle: Julie Hilaire - Univ Paris, Hop Lariboisiere, AP HP Nord, Serv Hematol Biol,CRMR MAT,Lab ADAMTS13,CRMR Mala, Paris, France
Clara Noizat - Univ Paris, Hop Lariboisiere, AP HP Nord, Serv Hematol Biol,CRMR MAT,Lab ADAMTS13,CRMR Mala, Paris, France
Minh-Toan Duong - Univ Paris, Hop Lariboisiere, AP HP Nord, Serv Hematol Biol,CRMR MAT,Lab ADAMTS13,CRMR Mala, Paris, France
Maxime Delrue - Univ Paris, Hop Lariboisiere, AP HP Nord, Serv Hematol Biol,CRMR MAT,Lab ADAMTS13,CRMR Mala, Paris, France
Dominique Herve - Univ Paris, Hop Lariboisiere, AP HP Nord, Serv Neurol,Ctr Reference Malad Vasc Rares Cervea, Paris, France
Alain Stepanian - Univ Paris, Hop Lariboisiere, AP HP Nord, Serv Hematol Biol,CRMR MAT,Lab ADAMTS13,CRMR Mala, Paris, France
Marie Neuwirth - Univ Paris, Hop Lariboisiere, AP HP Nord, Serv Hematol Biol,CRMR MAT,Lab ADAMTS13,CRMR Mala, Paris, France
Arezki Hadj-Ali - Univ Paris, Hop Lariboisiere, AP HP Nord, Serv Hematol Biol,CRMR MAT,Lab ADAMTS13,CRMR Mala, Paris, France
Berangere S. Joly - Univ Paris, Hop Lariboisiere, AP HP Nord, Serv Hematol Biol,CRMR MAT,Lab ADAMTS13,CRMR Mala, Paris, France
Agnes Veyradier - Univ Paris, Hop Lariboisiere, AP HP Nord, Serv Hematol Biol,CRMR MAT,Lab ADAMTS13,CRMR Mala, Paris, France
Virginie Siguret - Univ Paris, Hop Lariboisiere, AP HP Nord, Serv Hematol Biol,CRMR MAT,Lab ADAMTS13,CRMR Mala, Paris, France
Nicolas Beranger - Univ Paris, Hop Lariboisiere, AP HP Nord, Serv Hematol Biol,CRMR MAT,Lab ADAMTS13,CRMR Mala, Paris, France
Détails de publication: Annales de biologie clinique (Paris), Vol.79(4), pp.361-367
Éditeur: John Libbey Eurotext Ltd
Nombre de pages: 7
Identifiants: 99148711209311
Unité académique: Physiologie et Médecine Expérimentale du coeur et des muscles - PhyMedExp
Langue: English; French
Type de ressource: Journal article