LC-MS/MS for the Quantification of Tau and Phosphorylated Tau in Alzheimer's Disease Patients' CSF

Christophe Hirtz; Sylvain Lehmann; Laura Fichter; Stephane Moreau; Jerome Vialaret

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Article de revue

LC-MS/MS for the Quantification of Tau and Phosphorylated Tau in Alzheimer's Disease Patients' CSF

Christophe Hirtz, Sylvain Lehmann, Laura Fichter, Stephane Moreau et Jerome Vialaret

The Column, Vol.17(4), p.2

01/04/2021

Résumé

Alzheimer's disease

Analysis

Cerebrospinal fluid proteins

Diagnosis

Liquid chromatography

Mass spectrometry

Methods

Tau proteins

Quantification of tau proteoforms in cerebrospinal fluid (CSF) could be useful to help diagnose Alzheimer's disease (AD), other neurodegenerative diseases, and brain damage. In this article, LC-MS/MS results for tau and phosphorylated tau (pTau) are compared with in vitro diagnostic (IVD)-qualified immunoassay kits to distinguish between AD patients and control patients (1).

Indicateurs

1 Consultations de la notice

Détails

Titre: LC-MS/MS for the Quantification of Tau and Phosphorylated Tau in Alzheimer's Disease Patients' CSF
Créateurs - sans rôle: Christophe Hirtz
Sylvain Lehmann
Laura Fichter
Stephane Moreau
Jerome Vialaret
Détails de publication: The Column, Vol.17(4), p.2
Éditeur: Intellisphere, LLC
Identifiants: 99139951409311
Unité académique: Institut des Neurosciences de Montpellier - INM
Langue: English
Type de ressource: Journal article