Intraflagellar Transport Complex B Proteins Regulate the Hippo Effector Yap1 during Cardiogenesis

Marina Peralta; Laia Ortiz Lopez; Katerina Jerabkova; Tommaso Lucchesi; Benjamin Vitre; Dong Han; Laurent Guillemot; Chaitanya Dingare; Izabela Sumara; Nadia Mercader; Virginie Lecaudey; Benedicte Delaval; Sigolène Meilhac; Julien Vermot

doi:10.1016/j.celrep.2020.107932

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Intraflagellar Transport Complex B Proteins Regulate the Hippo Effector Yap1 during Cardiogenesis

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Intraflagellar Transport Complex B Proteins Regulate the Hippo Effector Yap1 during Cardiogenesis

Marina Peralta, Laia Ortiz Lopez, Katerina Jerabkova, Tommaso Lucchesi, Benjamin Vitre, Dong Han, Laurent Guillemot, Chaitanya Dingare, Izabela Sumara, Nadia Mercader, …

Cell Reports, Vol.32(3)

07/2020

DOI: https://doi.org/10.1016/j.celrep.2020.107932

Abstract

Highlights d IFT proteins restrict proepicardial and myocardial development d IFT proteins act independently of primary cilia in this process d IFT proteins modulate BMP signaling by tuning Yap1-Tead activity d IFT88 and IFT20 interact with YAP1 in the cytoplasm to set Yap1-Tead activity

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Title: Intraflagellar Transport Complex B Proteins Regulate the Hippo Effector Yap1 during Cardiogenesis
Creators - without role: Marina Peralta - Institut de génétique et de biologie moléculaire et cellulaire
Laia Ortiz Lopez - Institut de génétique et de biologie moléculaire et cellulaire
Katerina Jerabkova - Institut de génétique et de biologie moléculaire et cellulaire
Tommaso Lucchesi - Institut Pasteur
Benjamin Vitre - Université de Montpellier, Centre de Recherche en Biologie Cellulaire de Montpellier - CRBM
Dong Han - Délégation Paris 5
Laurent Guillemot - Délégation Paris 5
Chaitanya Dingare - Goethe University Frankfurt
Izabela Sumara - Institut de génétique et de biologie moléculaire et cellulaire
Nadia Mercader - University of Bern
Virginie Lecaudey - Goethe University Frankfurt
Benedicte Delaval - Université de Montpellier, Centre de Recherche en Biologie Cellulaire de Montpellier - CRBM
Sigolène Meilhac - Inserm
Julien Vermot - Imperial College London
Publication Details: Cell Reports, Vol.32(3)
Identifiers: 9933906109311
Academic Unit: Centre de Recherche en Biologie Cellulaire de Montpellier - CRBM
Language: English
Resource Type: Journal article
Local Fields: hal-02989229