Logo image
Se connecter
Innate immune recognition of breast tumor cells mediates CCL22 secretion favoring Treg recruitment within tumor environment
Article de revue   Avec comité de lecture

Innate immune recognition of breast tumor cells mediates CCL22 secretion favoring Treg recruitment within tumor environment

Christine Menetrier-Caux, Julien Faget, Cathy Biota, Michael Gobert, Jean-Yves Blay et Christophe Caux
Oncoimmunology, Vol.1(5), pp.759-761
01/08/2012
PMID: 22934274

Résumé

Immunology Life Sciences & Biomedicine Oncology Science & Technology
Regulatory T cells (Treg) have been reported of poor prognosis for overall survival in primary breast tumors (BT). As CCL22 plays a major role in Treg recruitment within primary BT we deciphered the mechanisms involved in the CCL22 production by breast epithelial tumor cells and propose herein the major role of their innate immune recognition in this production.

Indicateurs

1 Consultations de la notice

Détails

Logo image