Inhibition of the multidrug transporter P-glycoprotein improves seizure control in phenytoin-treated chronic epileptic rats

Erwin A VAN VLIET; Rosalinde VAN SCHAIK; Peter M Edelbroek; Sandra Redeker; Eleonora Aronica; Wytse J Wadman; Nicola Marchi; Annamaria Vezzani; Jan A Gorter

doi:10.1111/j.1528-1167.2006.00496.x

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Inhibition of the multidrug transporter P-glycoprotein improves seizure control in phenytoin-treated chronic epileptic rats

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Inhibition of the multidrug transporter P-glycoprotein improves seizure control in phenytoin-treated chronic epileptic rats

Erwin A VAN VLIET, Rosalinde VAN SCHAIK, Peter M Edelbroek, Sandra Redeker, Eleonora Aronica, Wytse J Wadman, Nicola Marchi, Annamaria Vezzani et Jan A Gorter

Epilepsia (Copenhagen), Vol.47(4), pp.672-680

04/2006

DOI: https://doi.org/10.1111/j.1528-1167.2006.00496.x

PMID: 16650133

Résumé

Anticonvulsants. Antiepileptics. Antiparkinson agents

Biological and medical sciences

Central nervous system

Central neurotransmission. Neuromudulation. Pathways and receptors

Fundamental and applied biological sciences. Psychology

Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy

Medical sciences

Nervous system (semeiology, syndromes)

Neurology

Neuropharmacology

Pharmacology. Drug treatments

Vertebrates: nervous system and sense organs

Indicateurs

1 Consultations de la notice

Détails

Titre: Inhibition of the multidrug transporter P-glycoprotein improves seizure control in phenytoin-treated chronic epileptic rats
Créateurs - sans rôle: Erwin A VAN VLIET - Epilepsy Institute of The Netherlands (SEIN), Heenistede, Netherlands
Rosalinde VAN SCHAIK - Swammerdam Institute for Life Sciences, Center for Neuroscience, Netherlands
Peter M Edelbroek - Epilepsy Institute of The Netherlands (SEIN), Heenistede, Netherlands
Sandra Redeker - Department of (Neuro) Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands
Eleonora Aronica - University of Amsterdam
Wytse J Wadman - Swammerdam Institute for Life Sciences, Center for Neuroscience, Netherlands
Nicola Marchi - Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri,, Milano, Italy
Annamaria Vezzani - Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri,, Milano, Italy
Jan A Gorter - Epilepsy Institute of The Netherlands (SEIN), Heenistede, Netherlands
Détails de publication: Epilepsia (Copenhagen), Vol.47(4), pp.672-680
Éditeur: Blackwell
Nombre de pages: 9
Identifiants: 99163096409311
Unité académique: Institut de Génomique Fonctionnelle - IGF
Langue: English
Type de ressource: Journal article