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Induced pluripotent stem cells: An unlimited source of organs for transplantation
Journal article   Peer reviewed

Induced pluripotent stem cells: An unlimited source of organs for transplantation

John de Vos and Said Assou
Clinics and Research in Hepatology and Gastroenterology, Vol.41(3), pp.249 - 253
06/2017
PMID: 27964840

Abstract

Organ production outside the human body could address the shortage of organs for transplantation. However, in vitro organ production is still a faraway perspective, particularly because of the difficulty in establishing an effective vascularization. A new emerging technology proposes to use carrier animals for the development of human organs. In this approach, induced pluripotent stem cells (iPSC) are injected in animal embryos to produce chimeric animals that contain autologous human organs.
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